((1-3-η3)-[2,3:3',4']-([3:3']-o-hydroxyphenyl)-5'-n-propyl(1'-phenylsulfonyl)-1',5'-dihydro-2'H-pyrrol-2'-one)-carbonylcyclopentadienyliron | 299915-53-0

• 英文名称: ((1-3-η3)-[2,3:3',4']-([3:3']-o-hydroxyphenyl)-5'-n-propyl(1'-phenylsulfonyl)-1',5'-dihydro-2'H-pyrrol-2'-one)-carbonylcyclopentadienyliron
• CAS: 299915-53-0
• 化学式: C₂₆H₂₅FeNO₅S
• 分子量: 519.401
• InChiKey: AAFHQZJVRQXZLT-NMRXSTGRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
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• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  4-[(η5-cyclopentadienyl)dicarbonyliron]-3-([(phenylsulfonyl)imino]methyl)-(2H)-chromene * 0.25CH2Cl2 、 水 、 丙基氯化镁 在 NaCl 作用下， 以 水 、 1,2-二氯乙烷 为溶剂， 以24%的产率得到((1-3-η3)-[2,3:3',4']-([3:3']-o-hydroxyphenyl)-5'-n-propyl(1'-phenylsulfonyl)-1',5'-dihydro-2'H-pyrrol-2'-one)-carbonylcyclopentadienyliron
  参考文献：
  名称：

  Reactions of (η⁵-C₅H₅)(CO)₂Fe-Substituted N-Sulfonyl Azadienes with C-Nucleophiles. A Route to 5-Substituted Dihydropyrrolones

  摘要：

  A variety of cyclic beta-[(eta(5)-C5H5)(CO)(2)Fe]-substituted N-sulfonyl azadienes 4 were pre pared: e.g., from the corresponding iron-substituted (Z)-enals and benzenesulfonamide. Reactions of these iron compounds with Grignard reagents or organolithiums gave 5-substituted alpha,beta-unsaturated N-sulfonyl gamma-lactams 5. In some cases the corresponding non-N-protected 5-substituted gamma-lactams 6 were isolated as well. Key steps of these reaction cascades are the initial 1,2-addition to the imine moiety and the subsequent carbonylation step. The reaction of the chromene-iron complex 4e with (allyl)MgCl gave the (eta(3)-allyl)iron-gamma-lactam complex 8a with a ring-opened chromene framework. This complex was structurally characterized by X-ray analysis.

  DOI：

  10.1021/om000235j