1,2-bis(2-(3-methyl-5-isoxazolyl)methoxyethoxy)benzene | 171826-63-4

• 英文名称: 1,2-bis(2-(3-methyl-5-isoxazolyl)methoxyethoxy)benzene
• 英文别名: 3-Methyl-5-[2-[2-[2-[(3-methyl-1,2-oxazol-5-yl)methoxy]ethoxy]phenoxy]ethoxymethyl]-1,2-oxazole
• CAS: 171826-63-4
• 化学式: C₂₀H₂₄N₂O₆
• 分子量: 388.42
• InChiKey: MNXBSNZUVYBXMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  28
• 可旋转键数：
  12
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  89
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,2-bis(2-(3-methyl-5-isoxazolyl)methoxyethoxy)benzene 在 platinum on activated charcoal 盐酸 、 氢气 作用下， 以 乙醇 为溶剂， 反应 5.0h， 生成 1,2-bis(1,4-dioxa-6,9-dioxononyl)benzene
  参考文献：
  名称：

  Cooperative Metal Ion Binding by Metal-Organized Crown Ether

  摘要：

  Host molecules which satisfy both facile synthesis and strong as well as selective binding of metal ions have been developed by introducing an idea of metal-assisted organization of linear molecules into crown ethers. For this purpose, an oligo(oxyethylene) prehost having two beta-diketone units in both terminal positions was synthesized. Intramolecular coordination of the two beta-ketones to divalent transition metals, Cu, Zn, or Ni, organized the linear prehost into a macrocyclic pseudo crown structure. The crystal structure of the Cu-organized host and K+ picrate complex was analyzed by X-ray crystallography. The structure elucidated indicated that the intramolecular coordination of beta-ketoenolate oxygens to the transition metal furnished an organized cavity into which the potassium cation was entrapped. The metal-organized crowns showed a good size-fit selectivity, characteristic of macrocycles, and a superior extraction efficiency when compared with dibenzo-18-crown-6 as a reference compound for the picrate extraction of alkali and alkaline earth metal cations. These characteristics have been ascribed to the existence of polar bonds between negatively charged enolate oxygens and transition metals and illustrates the power of the self-organization method in preparing the host.

  DOI：

  10.1021/ja00156a012
• 作为产物：
  描述：

  5-氯甲基-3-甲基异噁唑 、 O,O-双(2-羟基乙氧基)苯 以 四氢呋喃 为溶剂， 生成 1,2-bis(2-(3-methyl-5-isoxazolyl)methoxyethoxy)benzene
  参考文献：
  名称：

  Extractant for selectively extracting strontium from aqueous solution

  摘要：

  从含有锶的水溶液中选择性提取锶的萃取剂，包括以下结构式的1,2-苯基双(1,4-二氧戊基-6,8-二酮酸)金属络合物：##STR1## 其中M代表Cu(II)、Zn(II)或Ni(II)的金属离子。

  公开号：

  US05463099A1

文献信息

• US5463099A
  申请人：——

  公开号：US5463099A

  公开（公告）日：1995-10-31