1.2-((CH2)2OH)2-1.2-C2B10H10 | 23810-37-9

• 英文名称: 1.2-((CH2)2OH)2-1.2-C2B10H10
• 英文别名: 1,2-dicarba-closo-dodecaborane-1,2-diethanol；1,2-(HOCH2CH2)2-1,2-C2B10H10
• CAS: 23810-37-9
• 化学式: C₆H₂₀B₁₀O₂
• 分子量: 232.334
• InChiKey: QJOCVYMEOYLJKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  1.2-((CH2)2OH)2-1.2-C2B10H10 在 chromium(VI) oxide 、 溶剂黄146 作用下， 以 水 、 丙酮 为溶剂， 以41%的产率得到1,2-dicarba-closo-dodecaborane-1,2-diacetic acid
  参考文献：
  名称：

  碳硼烷的宿主-来宾化学：羧酸盐衍生物的合成及其与环糊精的结合

  摘要：

  已合成了多面体羧甲基碳硼烷（C 2 B 10 H 12）衍生物，包括单和双取代的o-，m-和p-异构体。这些衍生物与环糊精（CD；即α-，β-和γ-CD）的超分子主客体络合物已经在水中进行了研究。碳硼烷结合部分的球状结构及其疏水特性使其成为理想的识别位点，可与水溶液中的大环主体分子形成稳定的包合物。碳硼烷衍生物的结合亲和力在毫摩尔范围内（K a = 10 3 –10 4  m-1）具有不同大小的CD，并优先绑定到β-CD。

  DOI：

  10.1002/chem.201802134
• 作为产物：
  描述：

  环氧乙烷 、 1,2-dilithio-o-carborane 以 乙醚 为溶剂， 以35%的产率得到1.2-((CH2)2OH)2-1.2-C2B10H10
  参考文献：
  名称：

  Carboranes. III. Reactions of the Carboranes

  摘要：

  DOI：

  10.1021/ic50010a009

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: B: B-Verb.12, 4.6.1.1, page 1 - 23
  作者：

  DOI：——

  日期：——
• A New Series of Organoboranes. III. Some Reactions of 1,2-Dicarbaclovododecaborane(12) and its Derivatives
  作者：T. L. Heying、J. W. Ager、S. L. Clark、R. P. Alexander、S. Papetti、J. A. Reid、S. I. Trotz

  DOI：10.1021/ic50010a004

  日期：1963.12
• Zakharkin, L. I., Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1965, p. 138 - 140
  作者：Zakharkin, L. I.

  DOI：——

  日期：——
• Synthesis and Structural Characterization of Hydroxyethyl- and Alkoxyethyl-<i>o</i>-Carboranes and Their Alkali and Rare Earth Metal Complexes
  作者：Mak-Shuen Cheung、Hoi-Shan Chan、Zuowei Xie

  DOI：10.1021/om034081u

  日期：2004.2.1

  Facile and practical syntheses of 1,2-(HOCH2CH2)(2)-1,2-C2B10H10 (1), its derivatives 1,2-(ROCH2CH2)(2)-1,2-C2B10H10 (R = CH3 (2), CH2Ph (4)), and 1-(CH3OCH2CH2)-1,2-C2B10H11 (3) were reported. Treatment of 1 with excess K metal in THF gave, after fractional crystallization from acetone containing 18-crown-6 ether, two complexes, [nido-(HOCH2CH2)(OCH2CH2)C2B10H10}K(18-crown-6)}](n) (5) and [nido-(HOCH2CH2)(2)C2B9H10}K(18-crown-6)}](n) (6) in a molar ratio of 1:2. Reaction of 2 with MeOK in methanol afforded, after treatment with Me3NHCl, [Me3NH] [nido-(CH3OCH2CH2)(2)C2B9H10] (7). 2 reacted with excess Na metal in THF to yield [eta(6)-[(CH3OCH2CH2)(2)C2B10H10]Na}Na(THF)}](n) (8). Interactions of 2 with LnCl(3) in the presence of excess Li or Na metal gave, after recrystallization from a mixture of different solvents, half-sandwich 13-vertex closo-metallacarboranes [eta(7)-[(CH3OCH2CH2)(2)C2B10H10]Er}Na(CH3CN)(2)}](2) (9) and [eta(7)-[(CH3OCH2CH2)(2)C2B10H10]Y}Li(THF)(3)}](2) (10). Complexes [[[eta(7)-(CH3OCH2CH2)C2B10H11]Er(THF)}Na(CH3CN)(THF)}](2)](n) (11) and [[eta(7)-(CH3OCH2CH2)C2B10H11]Y(THF)}Na(THF)(3)}](2) (12) were prepared in a similar manner from the monosubstituted o-carborane 3, LnCl(3), and excess Na in THF. These complexes were characterized by various spectroscopic data, elemental analyses, and X-ray diffraction studies. Structural studies show that the Lewis base-functionalized sidearms have some effects on the coordination environments of the central metal atom through intramolecular interactions between the donor atoms of the sidearms and Lewis acidic metal ions, but do not change the gross structures of the 13-vertex lanthanacarboranes.