N-(3,4-dimethyl-2-thietanylidene)isopropylamine | 139633-25-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚氨硫酯类
• 英文名称: N-(3,4-dimethyl-2-thietanylidene)isopropylamine
• 英文别名: (3R,4R)-3,4-dimethyl-N-propan-2-ylthietan-2-imine
• CAS: 139633-25-3；139633-26-4
• 化学式: C₈H₁₅NS
• 分子量: 157.28
• InChiKey: AXHSXYSFIFDVLK-RNFRBKRXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  37.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-isopropyltiglylamide 在 劳森试剂 作用下， 以 苯 为溶剂， 反应 2.0h， 生成 N-(3,4-dimethyl-2-thietanylidene)isopropylamine
  参考文献：
  名称：

  Photochemical isomerization of N-monosubstituted .alpha.,.beta.-unsaturated thioamides to iminothietanes

  摘要：

  Photochemical isomerization of thiomethacryl-, thiotiglyl-, and thiocrotonamides gives iminothietanes, N-(2-thietanylidene)amines, in good yields. The iminothietanes reverted quantitatively to the starting materials on heating. Use of Michler's ketone or thioxanthone as sensitizers indicates that the photoelectric cyclization proceeds from the triplet excited state. Irradiation of N-benzylthiocinnamamide does not give an iminothietane, but only cis-trans isomerization that reached the photostationary state at cis/trans = 1.7.

  DOI：

  10.1021/jo00034a040

文献信息

• Photochemical isomerization of N-monosubstituted .alpha.,.beta.-unsaturated thioamides to iminothietanes
  作者：Masami Sakamoto、Tsutomu Ishida、Tsutomu Fujita、Shoji Watanabe

  DOI：10.1021/jo00034a040

  日期：1992.4

  Photochemical isomerization of thiomethacryl-, thiotiglyl-, and thiocrotonamides gives iminothietanes, N-(2-thietanylidene)amines, in good yields. The iminothietanes reverted quantitatively to the starting materials on heating. Use of Michler's ketone or thioxanthone as sensitizers indicates that the photoelectric cyclization proceeds from the triplet excited state. Irradiation of N-benzylthiocinnamamide does not give an iminothietane, but only cis-trans isomerization that reached the photostationary state at cis/trans = 1.7.