N-(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩并噻唑类
• 英文名称: N-(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)acetamide
• 化学式: C₇H₁₀N₂O₃S₂
• 分子量: 234.3
• InChiKey: AUNVKDYANYQYEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  109
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  tetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-imine 5,5-dioxide 、 乙酸酐 生成 N-(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)acetamide
  参考文献：
  名称：

  BEZUGLYJ, YU. V.;BOREJKO, V. K.;BYLINA, E. V.;TUXAR, A. A.;FOREMNAYA, V. +, FIZIOL. AKTIV. VESHCHESTVA,(1989) N1, S. 44-49

  摘要：

  DOI：

文献信息

• TARGETED BONE MARROW PROTECTION AGENTS
  申请人：Garlich Joseph R.

  公开号：US20090011975A1

  公开（公告）日：2009-01-08

  The invention provides a method of inhibiting cell death in a mammal. The method comprises administering to a mammal an effective amount of a composition comprising a cell protection factor covalently linked to a bone targeting agent via a linkage that is cleaved under physiological conditions, whereby the cell protection factor is released from the bone targeting agent in vivo to inhibit cell death. The invention further provides a compound comprising a cell protection factor covalently attached to a bone targeting agent via a linker that is cleaved under physiological conditions.
• BEZUGLYJ, YU. V.;BOREJKO, V. K.;BYLINA, E. V.;TUXAR, A. A.;FOREMNAYA, V. +, FIZIOL. AKTIV. VESHCHESTVA,(1989) N1, S. 44-49
  作者：BEZUGLYJ, YU. V.、BOREJKO, V. K.、BYLINA, E. V.、TUXAR, A. A.、FOREMNAYA, V. +

  DOI：——

  日期：——