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托烷生物碱

中文名称 英文名称 CAS号 化学式 结构式图片
—— 6-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-3-(2-methoxyethyl)-1H-benzimidazol-2-one —— C24H26FN3O3
6-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-3-(2-methoxyethyl)-1H-benzimidazol-2-one
—— (3R)-3-(benzotriazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]butan-1-one —— C23H25FN4O
(3R)-3-(benzotriazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]butan-1-one
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C18H19FN2OS
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
—— 3-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]quinazolin-4-one —— C23H22FN3O2
3-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]quinazolin-4-one
—— (3S)-3-(benzotriazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]butan-1-one —— C23H25FN4O
(3S)-3-(benzotriazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]butan-1-one
—— 2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-4-methylphthalazin-1-one —— C24H24FN3O2
2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-4-methylphthalazin-1-one
—— (2S)-3-(3,5-dimethylpyrazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-methylpropan-1-one —— C22H28FN3O
(2S)-3-(3,5-dimethylpyrazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-methylpropan-1-one
—— 4-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2H-phthalazin-1-one —— C23H22FN3O2
4-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2H-phthalazin-1-one
—— 1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2,2-dimethylpropan-1-one —— C18H24FNO
1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2,2-dimethylpropan-1-one
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-isoquinolin-1-ylmethanone —— C23H21FN2O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-isoquinolin-1-ylmethanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(furan-2-yl)methanone —— C18H18FNO2
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(furan-2-yl)methanone
—— 1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-(1H-indol-3-yl)ethanone —— C23H23FN2O
1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-(1H-indol-3-yl)ethanone
—— 7-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,3-dimethylpurine-2,6-dione —— C22H24FN5O3
7-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,3-dimethylpurine-2,6-dione
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-3-ylmethanone —— C19H19FN2O
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-pyridin-3-ylmethanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methylthiadiazol-5-yl)methanone —— C17H18FN3OS
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(4-methylthiadiazol-5-yl)methanone
—— [4-(3,5-dimethylpyrazol-1-yl)phenyl]-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C25H26FN3O
[4-(3,5-dimethylpyrazol-1-yl)phenyl]-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— (5S)-5-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-3-methyl-1,3-thiazolidine-2,4-dione —— C19H21FN2O3S
(5S)-5-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-3-methyl-1,3-thiazolidine-2,4-dione
—— 1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2,2-dimethylpropan-1-one —— C18H24FNO
1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2,2-dimethylpropan-1-one
—— 2-[3-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,1-dioxo-1,2-benzothiazol-3-one —— C23H23FN2O4S
2-[3-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-oxopropyl]-1,1-dioxo-1,2-benzothiazol-3-one
—— 2-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one —— C22H21FN2O4S
2-[2-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one
—— (2R)-3-(3,5-dimethylpyrazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-methylpropan-1-one —— C22H28FN3O
(2R)-3-(3,5-dimethylpyrazol-1-yl)-1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-methylpropan-1-one
—— cyclopentyl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C19H24FNO
cyclopentyl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone —— C22H20F4N4O
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
—— 2-(benzotriazol-1-yl)-1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone —— C21H21FN4O
2-(benzotriazol-1-yl)-1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethanone
—— 3-fluoro-4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]benzamide —— C21H20F2N2O2
3-fluoro-4-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]benzamide
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-thiophen-2-ylmethanone —— C18H18FNOS
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-thiophen-2-ylmethanone
—— 5-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1,3-dimethylbenzimidazol-2-one —— C23H24FN3O2
5-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1,3-dimethylbenzimidazol-2-one
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(3,4,5-trimethoxyphenyl)methanone —— C23H26FNO4
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(3,4,5-trimethoxyphenyl)methanone
—— 2,3-dihydro-1,4-benzodioxin-6-yl-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C22H22FNO3
2,3-dihydro-1,4-benzodioxin-6-yl-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 2-ethyl-4-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]phthalazin-1-one —— C25H26FN3O2
2-ethyl-4-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]phthalazin-1-one
—— 1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone —— C18H20FN3O2
1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone
—— 1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone —— C18H20FN3O2
1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone
—— cyclopentyl-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C19H24FNO
cyclopentyl-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1H-pyridazin-6-one —— C18H18FN3O2
3-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-1H-pyridazin-6-one
—— (3R)-3-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2,3-dihydroisoindol-1-one —— C23H23FN2O2
(3R)-3-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-2,3-dihydroisoindol-1-one
—— 1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-(tetrazol-1-yl)propan-1-one —— C17H20FN5O
1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-3-(tetrazol-1-yl)propan-1-one
—— 2,3-dihydro-1,4-benzodioxin-6-yl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C22H22FNO3
2,3-dihydro-1,4-benzodioxin-6-yl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— (4,5-dichloro-1,2-thiazol-3-yl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C17H15Cl2FN2OS
(4,5-dichloro-1,2-thiazol-3-yl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1,3-thiazol-4-yl)methanone —— C17H17FN2OS
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1,3-thiazol-4-yl)methanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1-methylsulfonylpiperidin-4-yl)methanone —— C20H27FN2O3S
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1-methylsulfonylpiperidin-4-yl)methanone
—— 1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-4-(3-oxo-2,4-dihydroquinoxalin-1-yl)butane-1,4-dione —— C25H26FN3O3
1-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-4-(3-oxo-2,4-dihydroquinoxalin-1-yl)butane-1,4-dione
—— (3,5-difluorophenyl)-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H18F3NO
(3,5-difluorophenyl)-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-thiophen-3-ylethanone —— C19H20FNOS
1-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-thiophen-3-ylethanone
—— 4-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-2H-phthalazin-1-one —— C22H20FN3O2
4-[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-8-carbonyl]-2H-phthalazin-1-one
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[4-(thietan-3-yloxy)phenyl]methanone —— C23H24FNO2S
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-[4-(thietan-3-yloxy)phenyl]methanone
—— [(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1,3-thiazol-4-yl)methanone —— C17H17FN2OS
[(1S,5S)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(1,3-thiazol-4-yl)methanone
—— 2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one —— C22H21FN2O4S
2-[2-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one
—— (3,5-difluorophenyl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H18F3NO
(3,5-difluorophenyl)-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— 2,1,3-benzothiadiazol-5-yl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone —— C20H18FN3OS
2,1,3-benzothiadiazol-5-yl-[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]methanone
—— [(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(5-hydroxypyridin-3-yl)methanone —— C19H19FN2O2
[(1R,5R)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-8-yl]-(5-hydroxypyridin-3-yl)methanone