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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 哌啶类

    哌啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)((1S,4S,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)amino)-2-azabicyclo[2,2,1]heptan-2-yl)methanone —— C21H18F4N6O
    (5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)((1S,4S,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)amino)-2-azabicyclo[2,2,1]heptan-2-yl)methanone
    —— (3-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone —— C23H19F4N5O
    (3-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone
    —— (5-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,4R,6R)-6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone —— C23H19F4N5O
    (5-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,4R,6R)-6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone
    —— (3-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone —— C22H18F4N6O
    (3-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone
    —— (3-fluoro-2-(pyrimidin-2-yl)phenyl)((1S,4R,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2,2,1]heptan-2-yl)methanone —— C23H18F4N4O2
    (3-fluoro-2-(pyrimidin-2-yl)phenyl)((1S,4R,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2,2,1]heptan-2-yl)methanone
    —— (5-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,6R)-6-[5-(trifluoromethyl)pyridin-2-yl]oxy-2-azabicyclo[2.2.1]heptan-2-yl]methanone —— C23H18F4N4O2
    (5-fluoro-2-pyrimidin-2-ylphenyl)-[(1S,6R)-6-[5-(trifluoromethyl)pyridin-2-yl]oxy-2-azabicyclo[2.2.1]heptan-2-yl]methanone
    —— Tert-butyl 6-(hydroxyimino)-2-azabicyclo[2.2.1]heptane-2-carboxylate —— C11H18N2O3
    Tert-butyl 6-(hydroxyimino)-2-azabicyclo[2.2.1]heptane-2-carboxylate
    —— (5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)((1S,4R,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2,2,1]heptan-2-yl)methanone —— C21H17F4N5O2
    (5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)((1S,4R,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2,2,1]heptan-2-yl)methanone
    —— (6R,10S)-11-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-3-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine —— C22H17ClF4N4O
    (6R,10S)-11-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-3-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine
    —— [4-methyl-2-(triazol-2-yl)phenyl]-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone —— C21H20F3N7O
    [4-methyl-2-(triazol-2-yl)phenyl]-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone
    —— (6R,10S)-11-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-3-pyridin-3-yl-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine —— C21H17ClF3N5O
    (6R,10S)-11-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-3-pyridin-3-yl-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine
    —— Benzyl 4-amino-4-(4-fluorophenyl)piperidine-1-carboxylate —— C19H21FN2O2
    Benzyl 4-amino-4-(4-fluorophenyl)piperidine-1-carboxylate
    —— Tert-butyl 6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptane-2-carboxylate —— C17H22F3N3O2
    Tert-butyl 6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptane-2-carboxylate
    —— [3-fluoro-2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone —— C22H19F4N5O2
    [3-fluoro-2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]-[(1S,4S,6R)-6-[[5-(trifluoromethyl)pyridin-2-yl]amino]-2-azabicyclo[2.2.1]heptan-2-yl]methanone
    —— (6S,10R)-11-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-3-pyridin-3-yl-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine —— C21H17ClF3N5O
    (6S,10R)-11-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-3-pyridin-3-yl-5,6,7,8,9,10-hexahydro-6,10-epimino[1,2,4]triazolo[4,3-a]azocine
    —— US9650358, Example 87 —— C38H32ClF2N5O2
    US9650358, Example 87
    —— 3-[7-(2-Carboxyethyl)-7-azaspiro[3.5]nonan-8-yl]propanoic acid —— C14H23NO4
    3-[7-(2-Carboxyethyl)-7-azaspiro[3.5]nonan-8-yl]propanoic acid
    —— Endo-2-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-6-carboxylic acid —— C12H19NO4
    Endo-2-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-6-carboxylic acid
    —— US9650358, Example 301 —— C30H31ClFN5O2
    US9650358, Example 301
    —— US9650358, Example 118 —— C33H33ClFN5O
    US9650358, Example 118
    —— 3-azidopropanoic acid;(3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid —— C23H30N4O4S2
    3-azidopropanoic acid;(3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid
    —— (1-(5-aminopyridazin-4-yl)piperidin-4-yl)(3,3-difluoroazetidin-1-yl)methanone —— C13H17F2N5O
    (1-(5-aminopyridazin-4-yl)piperidin-4-yl)(3,3-difluoroazetidin-1-yl)methanone
    —— racemic cis-2-{6-[(1-methyl-1H-pyrazol-3-yl)methoxy]-1-(4-piperidin-1-ylbenzyl)-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid —— C31H37N5O3
    racemic cis-2-{6-[(1-methyl-1H-pyrazol-3-yl)methoxy]-1-(4-piperidin-1-ylbenzyl)-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid
    —— methyl 3-((2-((tert-butoxycarbonyl)amino)-4-chloropyridin-3-yl)ethynyl)piperidine-1-carboxylate —— C19H24ClN3O4
    methyl 3-((2-((tert-butoxycarbonyl)amino)-4-chloropyridin-3-yl)ethynyl)piperidine-1-carboxylate
    —— 2-(2,4-dioxo-3-azabicyclo[3.1.0]hexan-3-yl)ethyl methyl fumarate —— C12H13NO6
    2-(2,4-dioxo-3-azabicyclo[3.1.0]hexan-3-yl)ethyl methyl fumarate
    —— (S)-tert-butyl 4-oxo-2-(((triisopropylsilyl)oxy)methyl)piperidine-1-carboxylate —— C20H39NO4Si
    (S)-tert-butyl 4-oxo-2-(((triisopropylsilyl)oxy)methyl)piperidine-1-carboxylate
    —— 2-[1-[[4-(3,3-Difluoropiperidin-1-yl)phenyl]methyl]-6-[(5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C33H36F2N4O3
    2-[1-[[4-(3,3-Difluoropiperidin-1-yl)phenyl]methyl]-6-[(5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— Tert-butyl 3-[[4-[(2-methoxypyridin-3-yl)amino]-3-methylmorpholin-2-yl]-pyrimidin-2-ylamino]piperidine-1-carboxylate —— C25H37N7O4
    Tert-butyl 3-[[4-[(2-methoxypyridin-3-yl)amino]-3-methylmorpholin-2-yl]-pyrimidin-2-ylamino]piperidine-1-carboxylate
    —— racemic cis-2-{1-[4-(4,4-difluoropiperidin-1-yl)benzyl]-6-[(1-methyl-1H-pyrazol-3-yl)methoxy]-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid —— C31H35F2N5O3
    racemic cis-2-{1-[4-(4,4-difluoropiperidin-1-yl)benzyl]-6-[(1-methyl-1H-pyrazol-3-yl)methoxy]-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid
    —— racemic cis-2-{1-[4-(3,3-difluoropiperidin-1-yl)benzyl]-6-[(5-methylpyridin-2-yl)methoxy]-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid —— C33H36F2N4O3
    racemic cis-2-{1-[4-(3,3-difluoropiperidin-1-yl)benzyl]-6-[(5-methylpyridin-2-yl)methoxy]-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid
    —— 2-[1-[[2-Fluoro-4-(4-fluoropiperidin-1-yl)phenyl]methyl]-6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C33H35F3N4O3
    2-[1-[[2-Fluoro-4-(4-fluoropiperidin-1-yl)phenyl]methyl]-6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— 2-[1-[[2-Fluoro-4-(4-methylpiperidin-1-yl)phenyl]methyl]-6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C34H38F2N4O3
    2-[1-[[2-Fluoro-4-(4-methylpiperidin-1-yl)phenyl]methyl]-6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— 2-[6-[(5-Methylpyridin-2-yl)methoxy]-1-[(4-piperidin-1-ylphenyl)methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C33H38N4O3
    2-[6-[(5-Methylpyridin-2-yl)methoxy]-1-[(4-piperidin-1-ylphenyl)methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— 2-[6-[(5-Methylpyrazin-2-yl)methoxy]-1-[[4-[4-(trifluoromethyl)piperidin-1-yl]phenyl]methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C33H36F3N5O3
    2-[6-[(5-Methylpyrazin-2-yl)methoxy]-1-[[4-[4-(trifluoromethyl)piperidin-1-yl]phenyl]methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— 2-[6-[(1-Methylpyrazol-3-yl)methoxy]-1-[(4-piperidin-1-ylphenyl)methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C31H37N5O3
    2-[6-[(1-Methylpyrazol-3-yl)methoxy]-1-[(4-piperidin-1-ylphenyl)methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— (1R,2S)-2-[6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-[(4-piperidin-1-ylphenyl)methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C33H37FN4O3
    (1R,2S)-2-[6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-[(4-piperidin-1-ylphenyl)methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— (1S*,2R*)-2-{6-[(5-methylpyridin-2-yl)methoxy]-1-(4-piperidin-1-ylbenzyl)-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid —— C33H38N4O3
    (1S*,2R*)-2-{6-[(5-methylpyridin-2-yl)methoxy]-1-(4-piperidin-1-ylbenzyl)-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid
    —— 3-[3-[[5-fluoro-6-morpholin-4-yl-2-[(2-oxo-1H-pyridin-3-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]-3-oxopropanenitrile —— C21H25FN8O3
    3-[3-[[5-fluoro-6-morpholin-4-yl-2-[(2-oxo-1H-pyridin-3-yl)amino]pyrimidin-4-yl]amino]piperidin-1-yl]-3-oxopropanenitrile
    —— racemic cis-2-{6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-(4-piperidin-1-ylbenzyl)-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid —— C33H37FN4O3
    racemic cis-2-{6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-(4-piperidin-1-ylbenzyl)-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid
    —— 2-ethyl-2-({6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-[4-(4-fluoropiperidin-1-yl)benzyl]-1H-benzimidazol-2-yl}methyl)butanoic acid —— C33H38F2N4O3
    2-ethyl-2-({6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-[4-(4-fluoropiperidin-1-yl)benzyl]-1H-benzimidazol-2-yl}methyl)butanoic acid
    —— 3-(dimethylaminomethylene)-1-(2-fluoroethyl)piperidin-4-one —— C10H17FN2O
    3-(dimethylaminomethylene)-1-(2-fluoroethyl)piperidin-4-one
    —— 2-ethyl-2-({6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-[4-(4-methylpiperidin-1-yl)benzyl]-1H-benzimidazol-2-yl}methyl)butanoic acid —— C34H41FN4O3
    2-ethyl-2-({6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1-[4-(4-methylpiperidin-1-yl)benzyl]-1H-benzimidazol-2-yl}methyl)butanoic acid
    —— 2-ethyl-2-({1-[2-fluoro-4-(4-methylpiperidin-1-yl)benzyl]-6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1H-benzimidazol-2-yl}methyl)butanoic acid —— C34H40F2N4O3
    2-ethyl-2-({1-[2-fluoro-4-(4-methylpiperidin-1-yl)benzyl]-6-[(3-fluoro-5-methylpyridin-2-yl)methoxy]-1H-benzimidazol-2-yl}methyl)butanoic acid
    —— (1R,2S)-2-[1-[[4-(4,4-difluoropiperidin-1-yl)phenyl]methyl]-6-[(5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C33H36F2N4O3
    (1R,2S)-2-[1-[[4-(4,4-difluoropiperidin-1-yl)phenyl]methyl]-6-[(5-methylpyridin-2-yl)methoxy]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— Tert-butyl 3-[(6-chloro-3-fluoromorpholin-2-yl)-pyrimidin-4-ylamino]piperidine-1-carboxylate —— C18H27ClFN5O3
    Tert-butyl 3-[(6-chloro-3-fluoromorpholin-2-yl)-pyrimidin-4-ylamino]piperidine-1-carboxylate
    —— Tert-butyl 3-[[6-(2-chloro-5-fluoromorpholin-4-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate —— C18H27ClFN5O3
    Tert-butyl 3-[[6-(2-chloro-5-fluoromorpholin-4-yl)pyrimidin-4-yl]amino]piperidine-1-carboxylate
    —— racemic cis-2-{1-[4-(4,4-difluoropiperidin-1-yl)benzyl]-6-[(5-methylpyridin-2-yl)methoxy]-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid —— C33H36F2N4O3
    racemic cis-2-{1-[4-(4,4-difluoropiperidin-1-yl)benzyl]-6-[(5-methylpyridin-2-yl)methoxy]-1H-benzimidazol-2-yl}cyclohexanecarboxylic acid
    —— 1-O-tert-butyl 4-O-ethyl 3-(2-propan-2-ylpyrazol-3-yl)piperidine-1,4-dicarboxylate —— C19H31N3O4
    1-O-tert-butyl 4-O-ethyl 3-(2-propan-2-ylpyrazol-3-yl)piperidine-1,4-dicarboxylate
    —— [(3S,5R)-1-azatricyclo[3.3.1.13,7]decan-4-yl] formate —— C10H15NO2
    [(3S,5R)-1-azatricyclo[3.3.1.13,7]decan-4-yl] formate
    —— (2S,3R)-2-[3-fluoro-2-(triazol-2-yl)phenyl]-2-methyl-3-[5-(trifluoromethyl)pyridin-2-yl]oxypiperidine-1-carbaldehyde —— C21H19F4N5O2
    (2S,3R)-2-[3-fluoro-2-(triazol-2-yl)phenyl]-2-methyl-3-[5-(trifluoromethyl)pyridin-2-yl]oxypiperidine-1-carbaldehyde