((tert-butyldimethylsilyl)OC17H6N3(O)2(tert-butyldimethylsilyl))PtCl(dimethyl sulfoxide) | 937379-32-3

• 英文名称: ((tert-butyldimethylsilyl)OC17H6N3(O)2(tert-butyldimethylsilyl))PtCl(dimethyl sulfoxide)
• CAS: 937379-32-3
• 化学式: C₃₁H₄₂ClN₃O₄PtSSi₂
• 分子量: 839.462
• InChiKey: KVLJYUSHCSGTCT-UHFFFAOYSA-L

反应信息

• 作为反应物：
  描述：

  ((tert-butyldimethylsilyl)OC17H6N3(O)2(tert-butyldimethylsilyl))PtCl(dimethyl sulfoxide) 在 四丁基氟化铵 作用下， 以 二氯甲烷 为溶剂， 生成 (HOC17H7N3(O)2)PtCl(dimethyl sulfoxide)
  参考文献：
  名称：

  Platinum Complex as a Nanomolar Protein Kinase Inhibitor

  摘要：

  A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3 alpha).

  DOI：

  10.1021/ic062055t
• 作为产物：
  描述：

  cis-dichlorobis(dimethylsulfoxide)platinum(II) 、 4-[Tert-butyl(dimethyl)silyl]-18-[tert-butyl(dimethyl)silyl]oxy-4,11,14-triazapentacyclo[11.7.0.02,6.07,12.015,20]icosa-1,6,8,10,12,15(20),16,18-octaene-3,5-dione 在 potassium carbonate 作用下， 以 甲醇 、 甲苯 为溶剂， 以60%的产率得到((tert-butyldimethylsilyl)OC17H6N3(O)2(tert-butyldimethylsilyl))PtCl(dimethyl sulfoxide)
  参考文献：
  名称：

  Platinum Complex as a Nanomolar Protein Kinase Inhibitor

  摘要：

  A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3 alpha).

  DOI：

  10.1021/ic062055t