| 302924-15-8

• CAS: 302924-15-8
• 化学式: C₄₄H₄₀Cl₂N₂P₂Ru
• 分子量: 830.739
• InChiKey: POFAOWHLEWYWPG-VXECBIRNSA-L

反应信息

• 作为产物：
  描述：

  tris(triphenylphosphine)ruthenium(II) chloride 、 N,N'-bis[o-(diphenylphosphino)benzylidene]-1R,2R-diiminocyclohexane 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  通过醇升级控制高级生物燃料合成：催化剂对正丁醇、仲丁醇或异丁醇的选择性

  摘要：

  用于生物燃料合成的催化剂技术：革新 Guerbet 化学——钌催化醇升级化学中配体结构和反应条件的变化改变了与可持续燃料相关的丁醇异构体之间的选择性。

  DOI：

  10.1002/cctc.202201410
• 作为试剂：
  描述：

  (9ci)-5-氧代-1-环戊烯-1-羧酸甲酯 、 2,3-二甲基-1,3-丁二烯 在 [RuCl₂(C₆H₁₀(NCHC₆H₄P(C₆H₅)2)2)] 、 triethyloxonium hexaflourophosphate 作用下， 以 二氯甲烷 为溶剂， 生成 (1S,6S)-1-methoxycarbonyl-3,4-dimethyl-9-oxo-bicyclo[4.3.0]oct-3-ene 、 (1R,6R)-1-methoxycarbonyl-3,4-dimethyl-9-oxo-bicyclo[4.3.0]oct-3-ene
  参考文献：
  名称：

  Asymmetric Diels−Alder Reactions of Unsaturated β-Ketoesters Catalyzed by Chiral Ruthenium PNNP Complexes

  摘要：

  Cyclic alpha-unsaturated beta-ketoesters undergo cycloaddition with di- and trisubstituted butadienes to give tetrahydro-1-indanone derivatives with up to 93% ee in the presence of a ruthenium catalyst formed by activation of [RuCl(2)(PNNP)] with (Et(3)P)PF(6) (2 equiv) (PNNP = (1S,2S)-N,N'-bis[o-(diphenylphosphino)benzylidene]cyclohexane-1,2-diamine). The protocol has been used to prepare the estrone derivative (8R, 13S, 14S)-13-tert-butoxycarbonyl-3-methoxy-7,8,1 2,13,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17(14H)-one as a single diastereoisomer with 85% yield and 99% ee after one crystallization step. Its absolute configuration, which has been determined by X-ray diffraction after reduction to the alcohol and esterification with camphanic chloride, is in agreement with the attack of the diene onto the open enantioface of the beta-keto ester (O-O) in the ruthenium complex [Ru(O-O)(PNNP)](2+), whose X-ray structure has been determined.

  DOI：

  10.1021/ja910039e