4,4-difluoro-8-(4-(p-tolylethynyl)phenyl)-1,3,5,7-tetramethyl-2-bromo-4-bora-3a,4a-diaza-s-indacene | 1031443-70-5

• 英文名称: 4,4-difluoro-8-(4-(p-tolylethynyl)phenyl)-1,3,5,7-tetramethyl-2-bromo-4-bora-3a,4a-diaza-s-indacene
• CAS: 1031443-70-5
• 化学式: C₂₈H₂₄BBrF₂N₂
• 分子量: 517.224
• InChiKey: LMIFPRUATMUZTL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  1-癸炔 、 4,4-difluoro-8-(4-(p-tolylethynyl)phenyl)-1,3,5,7-tetramethyl-2-bromo-4-bora-3a,4a-diaza-s-indacene 在 乙基溴化镁 作用下， 以 四氢呋喃 为溶剂， 反应 1.17h， 以70%的产率得到4,4-bis(dec-1-ynyl)-8-(4-(p-tolylethynyl)phenyl)-1,3,5,7-tetramethyl-2-bromo-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  Tailoring the Properties of Boron−Dipyrromethene Dyes with Acetylenic Functions at the 2,6,8 and 4-B Substitution Positions

  摘要：

  Substitution of F-Bodipy with alkynylaryl residues at boron, at the pyrrolic core or at the meso position, provides unique tri-, tetra-, and pentasubstituted dyes. Substitution at the (pyrrolic) 2,6-positions provides substantial red shifts with quantum yields in the 40-90% range and excited-state lifetimes of 3-7 ns. ON/OFF fluorescence switching can be produced by protonation of dibutylamino subunits.

  DOI：

  10.1021/ol800560b
• 作为产物：
  描述：

  4,4-difluoro-8-(4-iodophenyl)-1,3,5,7-tetramethyl-2-bromo-4-bora-3a,4a-diaza-s-indacene 、 4-甲苯基乙炔 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 二异丙胺 作用下， 以 四氢呋喃 为溶剂， 以81%的产率得到4,4-difluoro-8-(4-(p-tolylethynyl)phenyl)-1,3,5,7-tetramethyl-2-bromo-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  Tailoring the Properties of Boron−Dipyrromethene Dyes with Acetylenic Functions at the 2,6,8 and 4-B Substitution Positions

  摘要：

  Substitution of F-Bodipy with alkynylaryl residues at boron, at the pyrrolic core or at the meso position, provides unique tri-, tetra-, and pentasubstituted dyes. Substitution at the (pyrrolic) 2,6-positions provides substantial red shifts with quantum yields in the 40-90% range and excited-state lifetimes of 3-7 ns. ON/OFF fluorescence switching can be produced by protonation of dibutylamino subunits.

  DOI：

  10.1021/ol800560b