[Pd((4-OMe)C6H3CH=NC6H3-2,6-i-Pr2)(μ-Cl)2 | 1334680-68-0

• 英文名称: [Pd((4-OMe)C6H3CH=NC6H3-2,6-i-Pr2)(μ-Cl)2
• 英文别名: trans-μ-dichlorobis[(2,6-diisopropyl-N-(4-methoxybenzyliden-2-ido)aniline)palladium(II)]；[Pr((4-OMe)C6H3CH=NC6H3-2,6-iPr2)(μ-Cl)]2
• CAS: 1334680-68-0
• 化学式: C₄₀H₄₈Cl₂N₂O₂Pd₂
• 分子量: 872.579
• InChiKey: JFGFZABVXYLKJU-IYNRVBQRSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [Pd((4-OMe)C6H3CH=NC6H3-2,6-i-Pr2)(μ-Cl)2 在 sodium azide 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  的反应性μ叠氮和μ -thiocyanato桥接席夫碱钯环朝向芳香Ñ -heterocycles和膦

  摘要：

  的反应μ -叠氮基桥连的席夫碱钯环[钯{（4- R）C 6 H ^ 3 CH N-C 6 H ^ 3 -2,6-我-Pr 2 }（μ -N 3）] 2（R = H ； OMe）与1-甲基咪唑生成不同的构象单核环戊四环。络合物[Pd {（4-R）C 6 H 3 CH N–C 6 H 3 –2,6- i -Pr 2 }（μ- N 3）] 2（R ＝ H； OMe）与双齿1，2-双（4-吡啶基）-乙烯反应，得到单核环戊四环。[Pd {C 6 H 4 CH N–C 6 H 3 –2,6- i -Pr 2 }（μ- N 3）] 2与4,4'-联吡啶（bpy）的反应也产生了单核环戊四环。但是，[Pd {（4-MeO）C 6 H 3 CH N–C 6 H 3 –2,6- i -Pr 2 }（μ- N 3）]的反应2与4,4'-联吡啶形成4,4'-联吡啶桥联的双核palladacycle [Pd {（4-OMe）C

  DOI：

  10.1016/j.jorganchem.2012.10.033
• 作为产物：
  描述：

  sodium tetrachloropalladate(II) 、 N-(4-methoxy-benzylidene)-2',6'-diisopropyl-aniline 在 NaCH₃COO 作用下， 以 甲醇 为溶剂， 以55%的产率得到[Pd((4-OMe)C6H3CH=NC6H3-2,6-i-Pr2)(μ-Cl)2
  参考文献：
  名称：

  Facile synthesis and characterization of μ-chloro, azido, thiocyanato bridged cyclometallated Pd(II) containing Schiff-base ligands

  摘要：

  mu-Chloro bridged dinuclear cyclometallated Pd(II) complexes [Pd{(4-R)C6H3CH=NC6H3-2,6-i-Pr-2}(mu-Cl)](2) (R = H, OMe) were prepared by reaction of Na2PdCl4 with benzylideneanilines. Unexpectedly, Na2PdCl4 reacted with Schiff-bases bearing a furyl or a thienyl ring to give N-coordinated non-cyclometallated Pd(II) species [Pd(C4H3XCH=NC6H3-2,6-i-Pr-2)(2)Cl-2] (X = O, S). Treating [Pd{(4-R)C6H3CH=NC6H3-2,6-i-Pr-2}( mu-Cl)](2) (R = H, OMe) with an excess of NaN3 or NH4SCN generated mu-N-3 bridged or mu-SCN bridged cyclometallated Pd(II) complexes [Pd{(4-R)C6H3CH=NC6H3-2,6-i-Pr-2}(mu-Y)](2) (R = H, OMe; Y = N-3, NCS). The complexes were characterized by FTIR, NMR spectroscopy, elemental analysis and X-ray crystallography. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2011.06.003

文献信息

• Salicylaldimine‐bridged dinuclear cyclopalladated complexes: Synthesis, characterization and BSA binding studies
  作者：Yan Gao、Saimeng Zhang、Xiaoguang Li、Shuyao Jiang、Yajing Yang、Xiaohong Chang

  DOI：10.1002/aoc.5330

  日期：2020.2

  Salicylaldimine‐bridged dinuclear cyclopalladated complexes were synthesized by the reactions of cyclopalladated chloro dimers [Pd(4‐R)C6H3CH=N‐C6H3–2,6‐i‐Pr2}(μ‐Cl)]2 (R = H; OMe) with salen‐based bridging ligands. The complexes were characterized by FTIR, NMR spectroscopy, elemental analysis and X‐ray crystallography. The binding interaction of cyclopalladated complexes to bovine serum albumin (BSA)

  水杨醛亚胺桥接的双核环钯配合物是通过环钯的氯二聚体[Pd （4-R）C 6 H 3 CH = N-C 6 H 3 –2,6‐ i‐ Pr 2 }（μ‐ Cl）反应合成的] 2（R = H; OMe），具有基于salen的桥接配体。通过FTIR，NMR光谱，元素分析和X射线晶体学对复合物进行表征。通过紫外可见光谱，荧光和同步荧光光谱研究了环palpalated配合物与牛血清白蛋白（BSA）的结合相互作用。实验结果表明，这些Pd（II）配合物可以以高亲和力结合BSA，并通过静态或组合过程猝灭其固有荧光。Pd复合物与BSA的相互作用也影响色氨酸和酪氨酸残基的构象。
• Self-assembly of Schiff-base palladacycle-based discrete pseudo-macrocycles: Evidence for hemilability of oxalate ligand
  作者：Yuchun Jiang、Benzhi Li、Yu Wang、Daliang Liu、Ximing Song、Xiaohong Chang

  DOI：10.1016/j.jorganchem.2014.02.020

  日期：2014.6

  Bis-bidentate tetra-coordinated oxalato bridged binuclear Schiff-base palladacycles [PdC,N-k(2)-(4-R) C6H3CH=NC6H3-2,6-i-Pr-2](2)(mu-eta(2)-eta(2)-C2O4) (R = H; OMe) were synthesized. Reactions of mu-oxalato bridged Schiff-base palladacycles [PdC,N-k(2)-(4-R)C6H3CH=NC6H3-2,6-i-Pr-2](2)(mu-eta(2)-eta(2)-C2O4) (R = H; OMe) with 1,4-bis(diphenylphosphino)butane (dppb) and 1,4-bis(diphenylphosphino)pentane (dppp) generated discrete pseudo-macrocycles with 1,1 '-bicoordinated oxalato bridge. Unexpectedly, mu-oxalato bridged Schiff-base palladacycle [Pd(C,N-k(2)-C6H4CH-NC6H3-2,6-i-Pr-2)](2)(mu-eta(2)-eta(2)-C2O4) reacted with PPh3 to form unusual bidentate/monodentate tri-coordinated oxalato bridged binuclear cyclopalladated complex [Pd(C,N-k(2)-C6H4CH=NC6H3-2,6-i-Pr-2)(PPh3)](mu-eta(2)-eta(1)-C2O4)[Pd(C-k(1)-C6H4CH=NC6H3-2,6-i-Pr-2)(PPh3)]. (C) 2014 Elsevier B.V. All rights reserved.
• Synthesis, characterization and interaction with bovine serum albumin of cyclometallated Pd(II) complexes containing arylimine and salicylaldimine co-ligands
  作者：Xu-Dong Jin、Yajing Yang、Yuchun Jiang、Xiang Han、Xiaowen Wan、Daliang Liu、Xi-Ming Song、Xiaohong Chang

  DOI：10.1016/j.jorganchem.2015.04.050

  日期：2015.8

  Cyclometallated Pd(II) complexes containing arylimine and salicylaldimine co-ligands were synthesized by the reactions of cyclopalladated chloro dimers [Pd(4-R)C6H3CH=N-C6H3-2,6-i-Pr-2}(mu-Cl)](2) (R - H; OMe) with salen-based ligands derived from rimantadine. The complexes were characterized by FTIR, NMR spectroscopy, elemental analysis and X-ray crystallography. Interaction of cyclometallated Pd(II) complexes with BSA was studied by fluorescence and synchronous fluorescence spectroscopy. The fluorescence intensities of protein are decreased gradually with increasing concentration of complexes. In the synchronous fluorescence spectra of BSA at Delta lambda = 15 nm and Delta lambda = 60 nm, the fluorescence of intensities of protein also are decreased with increasing concentration of complexes. (C) 2015 Elsevier B.V. All rights reserved.
• Synthesis, reactivity and characterization of mono-, bi- and tri-nuclear Schiff-base palladacycles with aromatic N-heterocycles
  作者：Xiaohong Chang、Yu Wang、Yuchun Jiang、Yonglin Guo、Dandan Song、Ximing Song、Francis Verpoort

  DOI：10.1016/j.jorganchem.2012.04.026

  日期：2012.8

  Reactions of mu(2)-Chloro bridged cyclometallated Pd(II) complexes [Pd(4-R) C6H3CH=NC6H3-2,6-i-Pr-2}(mu-Cl)] (2) (R = H, OMe) with aromatic N-heterocycles such as 1-methylimidazole, 4,4'-bipyridyl (bpy), 1,2-bis(4-pyridyl)-ethene (bpe), 2,5-bis(4-pyridyl)-1,3,4-thiadiazole (bpt) and 2,4,6-tris-(4-pyridyl)-1,3,5-triazine (tpt), generated mononuclear complexes [Pd(4-R)C6H3CH=NC6H3-2,6-i-Pr-2}(L)(Cl)] (L = 1-methylimidazole, R = H, OMe), binuclear complexes [Pd(4-R)C6H3CH=NC6H3-2,6-i-Pr-2}(Cl)](2)(mu-Y) (R = H, OMe; Y = bpy, bpe, bpt) and trinuclear complexes [Pd(4-R) C6H3CH=NC6H3-2,6-i-Pr-2}(Cl)](3)(tpt) (R H, OMe). In contrast, the reaction of mu(2)-Chloro bridged cyclometallated Pd(II) complexes [Pd(4-R) C6H3CH=NC6H3-2,6-i-Pr-2}(mu-Cl)](2) (R = H, OMe) with 2 equiv of AgNO3 and followed with bpy, bpe, bpt to produce binuclear cyclometallated Pd(II) nitrato complexes [Pd(4-R) C6H3CH=NC6H3-2,6-i-Pr-2}(ONO2)](2)(mu-Y) (R H, OMe; Y bpy, bpe, bpt). Treatment of [Pd(4-R)C6H3CH=NC6H3-2,6-i-Pr-2}(Cl)](3)(tpt) (R = H, OMe) with an excess AgNO3 produced trinuclear cyclometallated Pd(II) nitrato complexes [Pd(4R)C6H3CH=NC6H3-2,6-i-Pr-2}(ONO2)](3)(tpt) (R H, OMe). All these complexes were fully characterized by FT-IR, NMR spectroscopy, elemental analysis and/or X-ray crystallography. (C) 2012 Elsevier B.V. All rights reserved.