(R)-[((R)-BINOL-N,N-dibenzyl-phosphoramidite-κP)CpRuCl(PPh3)] | 1160862-57-6

• 英文名称: (R)-[((R)-BINOL-N,N-dibenzyl-phosphoramidite-κP)CpRuCl(PPh3)]
• CAS: 1160862-57-6
• 化学式: C₅₇H₄₆ClNO₂P₂Ru
• 分子量: 975.468
• InChiKey: LZLRWYUJEBAFGA-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  thallium(I) hexafluorophosphate 、 (R)-[((R)-BINOL-N,N-dibenzyl-phosphoramidite-κP)CpRuCl(PPh3)] 以 氘代氯仿 为溶剂， 生成 [((R)-BINOL-N,N-dibenzyl-phosphoramidite-κP)CpRu(PPh3)]PF6
  参考文献：
  名称：

  Synthesis and structural characterization of new chiral mixed phosphine phosphoramidite complexes of ruthenium

  摘要：

  New phosphoramidite complexes of ruthenium chiral at the metal were synthesized, structurally characterized and their electrochemical and catalytic properties were studied. Reaction of the known chiral phosphoramidites (RO)(2) PNR'(2) (R = naphthyl, R' = CH3, 1a; R = naphthyl, R' = benzyl, 1b; R = octahydronaphthyl, R' = benzyl, 1c) with CpRu(PPh3)(2)Cl afforded the title compounds CpRu(PPh3)(1a-c)(Cl) (2a-c) in 46-74% isolated yields. Fractional crystallization of 2b and 2c afforded the corresponding diastereopure complexes which are chiral both at the metal and at the ligand. The molecular structures of 2b and 2c were determined, revealing a pseudo octahedral coordination geometry about the ruthenium center. Electrochemical studies by cyclic voltammetry showed reversible electrochemical behavior of the metal complexes 2a-c. The new metal complexes are catalytically active in the Mukaiyama aldol reaction (24 h, room temperature, 31-53% yield), but almost no enantiomeric excesses for the products were obtained. (c) 2008 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2008.09.003
• 作为产物：
  描述：

  二(三苯基膦)环戊二烯基氯化钌(II) 、 O,O'-(R)-(1,1'-dinaphthyl-2,2'-diyl)-N,N'-dibenzylphosphoramidite 以 氯仿 为溶剂， 以74%的产率得到(R)-[((R)-BINOL-N,N-dibenzyl-phosphoramidite-κP)CpRuCl(PPh3)]
  参考文献：
  名称：

  Synthesis and structural characterization of new chiral mixed phosphine phosphoramidite complexes of ruthenium

  摘要：

  New phosphoramidite complexes of ruthenium chiral at the metal were synthesized, structurally characterized and their electrochemical and catalytic properties were studied. Reaction of the known chiral phosphoramidites (RO)(2) PNR'(2) (R = naphthyl, R' = CH3, 1a; R = naphthyl, R' = benzyl, 1b; R = octahydronaphthyl, R' = benzyl, 1c) with CpRu(PPh3)(2)Cl afforded the title compounds CpRu(PPh3)(1a-c)(Cl) (2a-c) in 46-74% isolated yields. Fractional crystallization of 2b and 2c afforded the corresponding diastereopure complexes which are chiral both at the metal and at the ligand. The molecular structures of 2b and 2c were determined, revealing a pseudo octahedral coordination geometry about the ruthenium center. Electrochemical studies by cyclic voltammetry showed reversible electrochemical behavior of the metal complexes 2a-c. The new metal complexes are catalytically active in the Mukaiyama aldol reaction (24 h, room temperature, 31-53% yield), but almost no enantiomeric excesses for the products were obtained. (c) 2008 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2008.09.003