| 190836-00-1

• CAS: 190836-00-1
• 化学式: C₉H₁₆BOP
• 分子量: 182.01
• InChiKey: OFHUEBWBHBQHSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  ethyl Phenylphosphinate 以 四氢呋喃 为溶剂， 反应 160.0h， 生成 、 (1-hydroxy-1-methylethyl)phenylphosphinous acid borane ethyl ester
  参考文献：
  名称：

  在膦酸酯和膦酸酯衍生物中存在P–O和P–N键的情况下，P = O键的化学选择性还原

  摘要：

  使用市售BH 3络合物，无需伴随其酯键和酰胺键的断裂即可实现α-羟基和α-氨基膦酸/次膦酸衍生物中P = O键的化学选择性还原。还原涉及通过近端的OH或NH基团的分子内协助，从而能够优先去除磷酰氧。

  DOI：

  10.1002/ejoc.201801518

文献信息

• PH bond activation of primary phosphine-boranes: Access to α-hydroxy and α,α′-dihydroxyphosphine-borane adducts by uncatalyzed hydrophosphination of carbonyl derivatives
  作者：Karine Bourumeau、Annie-Claude Gaumont、Jean-Marc Denis

  DOI：10.1016/s0022-328x(96)06640-5

  日期：1997.2

  Primary P-phenyl and P-methyl phosphine-boranes 1 and 2 are prepared by complexation of the free phosphines with BH3 . SMe2. They are stable and can be purified by distillation. Under basic conditions, they lead selectively to secondary alkylphosphine-boranes and under neutral conditions to the corresponding mono- and bis-hydroxyphosphine-boranes 5 and 6. All these new compounds are purified by chromatography on silica gel. A competitive hydroboration induced by the decomplexation of BH3 is observed as a minor process. Conditions for the decomplexation of phosphine-borane adducts are presented.