1,3-bis((methylphenylphosphino-borane)methyl)benzene | 882176-76-3

• 英文名称: 1,3-bis((methylphenylphosphino-borane)methyl)benzene
• CAS: 882176-76-3；882176-77-4
• 化学式: C₂₂H₃₀B₂P₂
• 分子量: 378.05
• InChiKey: LLRPCAPZLBZFAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  Methyl-[[3-[[methyl(phenyl)phosphanyl]methyl]phenyl]methyl]-phenylphosphane 在 硼烷四氢呋喃络合物 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 生成 1,3-bis((methylphenylphosphino-borane)methyl)benzene
  参考文献：
  名称：

  Chan, Vincent S.; Chiu, Melanie; Bergman, Robert G., Journal of the American Chemical Society, 2009, vol. 131, p. 6021 - 6032

  摘要：

  DOI：

文献信息

• Development of the First P-Stereogenic PCP Pincer Ligands, Their Metallation by Palladium and Platinum, and Preliminary Catalysis
  作者：B. Scott Williams、Paulo Dani、Martin Lutz、Anthony L. Spek、Gerard van Koten

  DOI：10.1002/1522-2675(20011114)84:11<3519::aid-hlca3519>3.0.co;2-9

  日期：2001.11.14

  The potentially tridentate P-stereogenic [P*CP*] ligands 1,3-bis[(tert-butyl)(phenyl)phosphino]methyl}-benzene and 1,3-[bis[(tert-butyl)(phenyl) phosphino]methyl]-2-bromobenzene have been synthesized as the protected phosphine-borane adducts. Deprotection with a secondary amine affords the free phosphine ligand which can be metallated by Pd and Pt with standard metal synthons. Two of the resultant [P*CP*] metal complexes have been characterized by X-ray crystallography. The complexes exhibit a C-2-symmetric environment about the remaining binding site of the square-planar center, with t-Bu groups filling two quadrants of the open site. The Pd complexes can be converted by use of a Ag salt to the analogous aquo complex, which is catalytically active in the aldol condensation of methyl 2-isocyanoacetate and benzaldehyde. Preliminary results and comparisons with previously reported catalysts with more distal C-stereogenicity are presented.