cis-[PtCl2(C2HN2O(Me)(Ph)2)2] | 324765-00-6

• 英文名称: cis-[PtCl2(C2HN2O(Me)(Ph)2)2]
• 英文别名: trans-[PtCl2(N=C(Ph)O-N(Me)-C(H)Ph)2]；trans-[PtCl2(C2HN2O(Me)(Ph)2)2]
• CAS: 324765-00-6
• 化学式: C₃₀H₂₈Cl₂N₄O₂Pt
• 分子量: 742.564
• InChiKey: IGQRRNLOMCXVAR-BRACKONXSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  cis-[PtCl2(C2HN2O(Me)(Ph)2)2] 、 氯 以 氘代氯仿 为溶剂， 以99%的产率得到trans-[PtCl4(N=C(Ph)O-N(Me)-C(H)Ph)2]
  参考文献：
  名称：

  [2 + 3] Cycloaddition of Nitrones to Platinum-Bound Organonitriles:  Effect of Metal Oxidation State and of Nitrile Substituent

  摘要：

  The ligated benzonitriles in the platinum(II) complex [PtCl2(PhCN)(2)] undergo metal-mediated [2+3] cycloaddition with nitrones -ON+(R-3)=C(R-1)(R-2) [R-1/R-2/R-3 = H/Ph/Me, H/p-MeC6H4/Me, H/Ph/CH2Ph] to give Delta (4)-1,2,4-oxadiazoline complexes, [PtCl2{N=C(Ph)O-N(R-3)-C(R-1)(R-2)}(2)] (2a, 4a, 6a), as a 1:1 mixture of two diastereoisomers, in 60-75%, while [PtCl2(MeCN)(2)] is inactive toward the addition. However, a strong activation of acetonitrile was reached by application of the platinum(IV) complex [PtCl4(MeCN)(2)] and both [PtCl4(RCN)(2)] (R = Me, Ph) react smoothly with various nitrones to give [PtCl4{N=C(R)O-N(R-3)-C(R-1)(R-2)}(2)] (1b-6b). The latter were reduced to the corresponding platinum(II) complexes [PtCl2{N=C(R)O-N(R-3)-C(R-1)(R-2)}(2)] (1a-6a) exhibit different kinetic labilities, and liberation of the Delta (4)-1,2,4-oxadiazolines by substitution with 1,2-bis(diphenylphosphino)ethane (dppe) in CDCl3 proceeds at different rates to give free N=C(R)O-N(R-3)-C(R-1)(R-2) and [PtCl2(dppe)] in almost quantitative NMR yield. All prepared compounds were characterized by elemental analyses, FAB mass spectrometry, and IR and H-1, C-13{H-1}, and 195 Pt (metal complexes) NMR spectroscopies; X-ray structure determination of the first (Delta (4)-1,2,4-oxadiazoline)Pt(II) complexes was performed for (S,S)/(R,R)-rac-[PtCl2{N=C(Me)O-C(H)Ph-2}(2)] (1a) (a = 9.3562(4), b = 9.8046(3), c = 13.1146(5) Angstrom; alpha = 76.155(2), beta = 83.421(2), gamma = 73.285(2)degrees; V = 1117.39(7) Angstrom (3); triclinic P (1) over bar, Z = 2), (R,S)-meso-[PtCl2-(N=C(Ph)O-N(Me)-C(H)Ph)(2)] (2a) (a = 8.9689(9), b = 9.1365(5), c = 10.1846(10) Angstrom; alpha = 64.328(6), beta = 72.532(4), gamma = 67.744(6)degrees; V = 686.82(11) Angstrom (3); triclinic, P (1) over bar, Z = 1), (S,S)/(R,R)-rac-[PtCl2(N=C(Me)O-N(Me)-C(H)(p-C6H4Me))(2)] (3a) (a = 11.6378(2), b = 19.0767(7), c = 11.5782(40 Angstrom; beta = 111.062(2)degrees; V = 2398(13) Angstrom (3); monoclinic, P2(1)/c, Z = 4), and (S,S)/(R,R)-rac-[PtCl2(N=C(Me)O-N(CH2Ph)-C(H)Ph)-C(H)Ph-2] (5a) (a = 10.664(2), b = 10.879(2), c = 14.388(3) Angstrom; alpha = 73.11(3), beta = 78.30(3), gamma = 88.88(30 degrees; V = 1562.6(6) Angstrom (3); triclinic, P (1) over bar, Z = 2).

  DOI：

  10.1021/ic000477b
• 作为产物：
  描述：

  trans-bis(benzonitrile)dichloroplatinum(II) 以 二氯甲烷 、 氯仿 为溶剂， 生成 cis-[PtCl2(C2HN2O(Me)(Ph)2)2]
  参考文献：
  名称：

  硝酮与[PtCl 2（PhCN）2 ]的反应中的配体识别。在热和微波条件下选择性生成单恶二唑啉和混合的双恶二唑啉配合物

  摘要：

  [2 + 3] 环加成 的硝酮 腈 配体在配合物中顺式或反式[PtCl 2（PhCN）2 ]发生在配体并允许选择性合成顺式或反式[PtCl 2（恶二唑啉）（PhCN）]复合物。微波辐射显着提高了环加成的反应速率，并且相对于热条件进一步有利于对单环加成物的选择性，因为第一环加成的加速程度高于第二环加成的程度。所述的反应反式与来自用于第一环加成步骤中的一个硝酮不同取代单-恶二唑啉络合物可以访问该组合物的混合双-恶二唑啉化合物反式- [氯铂酸2（恶二唑啉-a）的（二唑啉-B）] 。对应的顺式配置的复合体，但是不会进一步进行 环加成。所描述的所有反应均在铂中心附近不发生立体化学异构化的情况下发生，而与加热或微波加热无关。

  DOI：

  10.1039/b309847h