[Pt^II(4'-chloro-2,2':6'',2''-terpyridine)Cl]Cl | 355423-23-3

• 英文名称: [Pt^II(4'-chloro-2,2':6'',2''-terpyridine)Cl]Cl
• 英文别名: [Pt^II(Clterpy)Cl]Cl；[PtCl(4-chloro-2,2':6',2''-terpyridine)]Cl；[PtCl(Cl-4-terpy)]Cl
• CAS: 355423-23-3
• 化学式: C₁₅H₁₀Cl₃N₃Pt
• 分子量: 533.703
• InChiKey: QUWGSVDVICAFIG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [Pt^II(4'-chloro-2,2':6'',2''-terpyridine)Cl]Cl 、 乙腈 在 silver trifluoromethanesulfonate 作用下， 以 乙腈 为溶剂， 反应 3.0h， 生成 [Pt^II(4'-chloro-2,2':6'',2''-terpyridine)(CH₃CN)]Cl
  参考文献：
  名称：

  Caffeine derived platinum(II) N-heterocyclic carbene complexes with multiple anti-cancer activities

  摘要：

  Organometallic platinum(II) terpyridine complexes with a caffeine derived N-heterocyclic carbene (NHC) ligand were investigated as possible anti-cancer drugs in comparison to analogs, which contain N-coordinated theobromine. In general the carbene complexes displayed significantly higher biological activity than the theobromine analogs. In particular, the caffeine derived organometallic platinum(II) complex [PtII(2,20: 60,200-terpyridine) (1,3,7,9-tetramethylxanthine-8-ylidene)](PF6) 2 (1) displayed very promising cytotoxic activity towards several cancer cell lines, and showed in-vitro anti-angiogenic effects at sub-cytotoxic concentrations. Moreover, it induced neural differentiation-like morphological changes in breast adenocarcinoma (MCF-7) cells. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2014.10.041
• 作为产物：
  描述：

  dichloro( 1,5-cyclooctadiene)platinum(ll) 、 4′-(4-氯苯基)-2, 2′:6′, 2″-三联吡啶 以 甲醇 、 二氯甲烷 为溶剂， 反应 3.0h， 生成 [Pt^II(4'-chloro-2,2':6'',2''-terpyridine)Cl]Cl
  参考文献：
  名称：

  选择性和合作配体结合反平行人类端粒DNA G四联体。

  摘要：

  寻找特异性结合特定G-四链体核酸结构的配体对于设想对基因表达或端粒维持具有特定作用的分子或设想结构特异性的分子探针尤为重要。在自然条件下使用电喷雾质谱，我们揭示了铜II的高度合作和选择性2：1结合甲苯基吡啶与人类端粒G-四链体的复合物。圆二色性和不同序列亲和力的比较表明，对具有对角线环和/或宽-中-窄-中凹槽宽度顺序的反平行结构有明显的偏爱。协同性归因于多态端粒G-四链体序列的构象变化，当两个配体结合后，它们优选转化为反平行的三重四元体拓扑。

  DOI：

  10.1002/chem.201601937

文献信息

• Optical sensing of aqueous nitrate anion by a platinum(<scp>ii</scp>) triimine salt based solid state material
  作者：Amie E. Norton、Mahmood Karimi Abdolmaleki、Logan Andriot、Christina Cashen、Jeanette A. Krause、William B. Connick、Sayandev Chatterjee

  DOI：10.1039/d2cc04732b

  日期：——

  Selective and quantitative measurement of aqueous nitrate (NO₃⁻) anion is achieved using solid [Pt(Cl-4-tpy)Cl]ClO₄ salt (Cl-4-tpy = 4-chloro-2,2′:6′2′′-terpyridine), and as the salt supported on controlled porous glass.

  使用固体[Pt(Cl-4-tpy)Cl]ClO4盐（Cl-4-tpy = 4-氯-2,2′：6′2′′-三吡啶）以及作为控制多孔玻璃支撑的盐，可以实现对水中硝酸盐（NO3-）离子的选择性和定量测量。
• A highly selective vapochromic methanol sensor based on one step synthesis of a simple platinum terpyridine complex
  作者：Pingwu Du

  DOI：10.1016/j.ica.2009.12.054

  日期：2010.4

  A novel and simple luminescent methanol sensor, [Pt(Cl-4-terpy)Cl]Cl (2) (Cl-4-terpy = 4-Chloro-2,2':6',2 ''-terpyridine), has been synthesized in good yield over 85%. Complex 2 was studied spectroscopically in both fluid solution and solid state. At room temperature, it is observed that 2 is weak emissive maximized at 612 nm in fluid solution and brightly luminescent maximized at 655 nm in the solid state. At 77 K, the solid state of 2 shows different properties, with two obvious peaks maximized at 590 and 675 nm. The complex exhibits reversible vapochromic behavior upon exposure to methanol vapors, changing color from red to yellow, with a blue shift in the emission from 655 to 615 nm, resulting from the disruption of intermolecular Pt center dot center dot center dot Pt interactions by methanol vapor. The vapochromic sensor also shows high selectivity for only methanol vapors among all the general available volatile organic compounds (VOCs) in the lab, even in the presence of water, and fast response (color change in less than 1 s). (C) 2010 Elsevier B.V. All rights reserved.