aquachlorido(pyrrolidinedithiocarbamato-/kappa.2-S,S')platinum(II) | 1346685-80-0

• 英文名称: aquachlorido(pyrrolidinedithiocarbamato-/kappa.2-S,S')platinum(II)
• CAS: 1346685-80-0
• 化学式: C₅H₁₀ClNOPtS₂
• 分子量: 394.805
• InChiKey: SZXADLRURALHHG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  aquachlorido(pyrrolidinedithiocarbamato-/kappa.2-S,S')platinum(II) 、 二甲基亚砜 以 二甲基亚砜 为溶剂， 生成 [PtCl(pyrrolidinedithiocarbamate)(dimethyl sulfoxide)]
  参考文献：
  名称：

  Synthesis, crystal structure and antimicrobial studies of chlorido(dimethylsulfoxide-κS)(pyrrolidinedithiocarbamato-κ2S,S/)platinum(II)

  摘要：

  Platinum(II) complexes, [Pt(PDTC)(H2O)Cl] and [Pt(PDTC)(DMSO)Cl] (1) (PDTC = pyrrolidinedithiocarbamate) have been prepared and characterized by IR, NMR and X-ray crystallographic methods. In the crystal structure of 1 the central platinum atom is coordinated to two sulfur atoms of PDTC, one sulfur atom of DMSO and one chloride ion adopting a square planar geometry with the average cis and trans bond angles of 90.00 degrees and 171.62 degrees respectively. The H-1 and C-13 NMR spectral data indicate the coordination of both PDTC and DMSO to platinum(II). The title complex was screened for antimicrobial effects and the results show that it exhibits significant activity against gram-negative bacteria (E. coli, P. aeruginosa), while the activities are moderate against molds (A. niger, P. citrinum) and yeasts (C. albicans, S. serevisaiae). (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2011.09.021
• 作为产物：
  描述：

  1-吡咯烷二硫代氨基甲酸 、 potassium tetrachloroplatinate(II) 、 水 以 甲醇 、 水 为溶剂， 以50%的产率得到aquachlorido(pyrrolidinedithiocarbamato-/kappa.2-S,S')platinum(II)
  参考文献：
  名称：

  Synthesis, crystal structure and antimicrobial studies of chlorido(dimethylsulfoxide-κS)(pyrrolidinedithiocarbamato-κ2S,S/)platinum(II)

  摘要：

  Platinum(II) complexes, [Pt(PDTC)(H2O)Cl] and [Pt(PDTC)(DMSO)Cl] (1) (PDTC = pyrrolidinedithiocarbamate) have been prepared and characterized by IR, NMR and X-ray crystallographic methods. In the crystal structure of 1 the central platinum atom is coordinated to two sulfur atoms of PDTC, one sulfur atom of DMSO and one chloride ion adopting a square planar geometry with the average cis and trans bond angles of 90.00 degrees and 171.62 degrees respectively. The H-1 and C-13 NMR spectral data indicate the coordination of both PDTC and DMSO to platinum(II). The title complex was screened for antimicrobial effects and the results show that it exhibits significant activity against gram-negative bacteria (E. coli, P. aeruginosa), while the activities are moderate against molds (A. niger, P. citrinum) and yeasts (C. albicans, S. serevisaiae). (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2011.09.021