3-acyl-6-ferrocenyl-2-methyl-5,6-dihydropyran | 1622255-75-7

• 英文名称: 3-acyl-6-ferrocenyl-2-methyl-5,6-dihydropyran
• CAS: 1622255-75-7
• 化学式: C₁₈H₂₀FeO₂
• 分子量: 324.203
• InChiKey: UWGSAXYYNBAUQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 乙烯基二茂铁 、 乙酰丙酮 以 乙腈 为溶剂， 反应 3.0h， 以95%的产率得到3-acyl-6-ferrocenyl-2-methyl-5,6-dihydropyran
  参考文献：
  名称：

  A Facile Synthesis and Ring-Opening Reactions of Novel 2-Ferrocenyl-3,4-dihydropyrans

  摘要：

  A series of novel 2-ferrocenyl-3,4-dihydropyrans were synthesized in good to excellent yields through three-component reaction of vinylferrocene, 1,3-dicarbonyl compound and formaldehyde near room temperature under catalyst-free conditions. The obtained ferrocenyl dihydropyrans can also react readily with indole in the presence of alum, providing a ring-opening product in high yield, and this result opens an effective way to access a new class of complex ferrocenyl derivatives.

  DOI：

  10.3987/com-14-12977