[(HOC17H7N3(O)2)Pt(2-bromo-5-fluoropyridine)(5-hydroxy-2-methylpyridine)]PF6 | 937379-45-8

• 英文名称: [(HOC17H7N3(O)2)Pt(2-bromo-5-fluoropyridine)(5-hydroxy-2-methylpyridine)]PF6
• CAS: 937379-45-8
• 化学式: C₂₈H₁₈BrFN₅O₄Pt*F₆P
• 分子量: 927.429
• InChiKey: KTRJEOCLGUVXNQ-UHFFFAOYSA-M

反应信息

• 作为产物：
  描述：

  2-溴-5-氟吡啶 、 [(HOC17H7N3(O)2)Pt(acetonitrile)(5-hydroxy-2-methylpyridine)]PF6 以 丙酮 为溶剂， 生成 [(HOC17H7N3(O)2)Pt(2-bromo-5-fluoropyridine)(5-hydroxy-2-methylpyridine)]PF6
  参考文献：
  名称：

  Platinum Complex as a Nanomolar Protein Kinase Inhibitor

  摘要：

  A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3 alpha).

  DOI：

  10.1021/ic062055t