pyridinium 1-carbamoyl-1-[(methylthio)thiocarbonyl]methylide | 1210317-10-4

• 英文名称: pyridinium 1-carbamoyl-1-[(methylthio)thiocarbonyl]methylide
• CAS: 1210317-10-4
• 化学式: C₉H₁₀N₂OS₂
• 分子量: 226.323
• InChiKey: NOYCYMMDNYVIKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  pyridinium 1-carbamoyl-1-[(methylthio)thiocarbonyl]methylide 、 碘甲烷 以 丙酮 为溶剂， 反应 24.0h， 生成 1-[1-carbamoyl-2,2-bis(methylthio)vinyl]pyridinium iodide
  参考文献：
  名称：

  A New Approach to Imidazo[1,2-a]pyridine Derivatives and Their Application to the Syntheses of Novel 2H-Pyrano[2’,3’:4,5]imidazo[1,2-a]pyridin-2-one Derivatives

  摘要：

  3-[Bis(methylthio)methylene]-2(3H)-imidazo[1,2-a]pyridinones were prepared from the S-alkylation of pyridinium 1-[1-carbamoyl-1-[(methylthio) thiocarbonyl]]methylides with methyl iodide followed by the alkaline treatment of the resulting pyridinium salts. The reactions of these 3-methylene-2(3H)-imidazo[1,2-a]pyridinones with some ethyl cyano- or acyl-substituted acetates in the presence of a base did not afford the initially expected 2H-pyrano[2',3':4,5]imidazo[1,2-a]pyridine-2-one derivatives, but, instead of them, provided ethyl 3[2-hydroxyimidazo[1,2-a]pyridin-3-yl]acrylates. The thermolyses of these acrylates without any solvent under reduced pressure gave the corresponding 2H-pyrano[2',3':4,5]imidazo[1,2-a]pyridine-2-one derivatives.

  DOI：

  10.3987/com-09-s(s)41
• 作为产物：
  描述：

  二硫化碳 、 1-(氨甲酰甲基)吡啶氯 、 硫酸二甲酯 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成 pyridinium 1-carbamoyl-1-[(methylthio)thiocarbonyl]methylide
  参考文献：
  名称：

  A New Approach to Imidazo[1,2-a]pyridine Derivatives and Their Application to the Syntheses of Novel 2H-Pyrano[2’,3’:4,5]imidazo[1,2-a]pyridin-2-one Derivatives

  摘要：

  3-[Bis(methylthio)methylene]-2(3H)-imidazo[1,2-a]pyridinones were prepared from the S-alkylation of pyridinium 1-[1-carbamoyl-1-[(methylthio) thiocarbonyl]]methylides with methyl iodide followed by the alkaline treatment of the resulting pyridinium salts. The reactions of these 3-methylene-2(3H)-imidazo[1,2-a]pyridinones with some ethyl cyano- or acyl-substituted acetates in the presence of a base did not afford the initially expected 2H-pyrano[2',3':4,5]imidazo[1,2-a]pyridine-2-one derivatives, but, instead of them, provided ethyl 3[2-hydroxyimidazo[1,2-a]pyridin-3-yl]acrylates. The thermolyses of these acrylates without any solvent under reduced pressure gave the corresponding 2H-pyrano[2',3':4,5]imidazo[1,2-a]pyridine-2-one derivatives.

  DOI：

  10.3987/com-09-s(s)41