chlorido(5,10,15,20-tetramesitylporphyrinato(1-))oxoiron(IV) | 77742-79-1

• 英文名称: chlorido(5,10,15,20-tetramesitylporphyrinato(1-))oxoiron(IV)
• 英文别名: (5,10,15,20-tetramesitylporphyrinato(1+))Fe(IV)OCl；FeO(TMP)Cl
• CAS: 77742-79-1；95724-71-3
• 化学式: C₅₆H₅₂ClFeN₄O
• 分子量: 888.355
• InChiKey: RMSJPGZCIHBKHD-NJEFQPFRSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  chlorido(5,10,15,20-tetramesitylporphyrinato(1-))oxoiron(IV) 在 cyclooctene 作用下， 以 二氯甲烷 为溶剂， 生成 5,10,15,20-tetra(2',4',6'-trimethylphenyl)porphyrinatoiron(III) chloride
  参考文献：
  名称：

  Effect of the Axial Ligand on the Reactivity of the Oxoiron(IV) Porphyrin π-Cation Radical Complex: Higher Stabilization of the Product State Relative to the Reactant State

  摘要：

  The proximal heme axial ligand plays an important role in tuning the reactivity of oxoiron(IV) porphyrin pi-cation radical species (compound I) in enzymatic and catalytic oxygenation reactions. To reveal the essence of the axial ligand effect on the-reactivity, we investigated it from a thermodynamic viewpoint. Compound I model complexes, (TMP+center dot)(FeO)-O-IV(L) (where TMP is 5,10,15,20-tetrarnesitylporphyrin and TMP+center dot is its pi-cation radical), can be provided with altered reactivity by changing the identity of the axial ligand, but the reactivity is not correlated with spectroscopic data (nu(Fe=O), redox potential, and so on) of (TMP+center dot)(FeO)-O-IV(L). Surprisingly, a clear correlation was found between the reactivity of (TMP+center dot)(FeO)-O-IV(L) and the Fe-II/Fe-III redox potential of (TMP)(FeL)-L-III, the final reaction product. This suggests that the thermodynamic stability of (TMP)(FeL)-L-III is involved in the mechanism of the axial ligand effect. Axial ligand-exchange experiments and theoretical calculations demonstrate a linear free-energy relationship, in which the axial ligand modulates the reaction free energy by changing the thermodynamic stability of (TMP)Fe-III(L) to a greater extent than (TMP+center dot)(FeO)-O-IV(L). The linear free energy relationship could be found for a wide range of anionic axial ligands and for various types of reactions, such as epoxidation, demethylation, and hydrogen abstraction reactions. The essence of the axial ligand effect is neither the electron donor ability of the axial ligand nor the electron affinity of compound I, but the binding ability of the axial ligand (the stabilization by the axial ligand). An axial ligand that binds more strongly makes (TMP)Fe-III(L) more stable and (TMP+center dot)(FeO)-O-IV(L) more reactive. All results indicate that the axial ligand controls the reactivity of compound I (the stability of the transition state) by the stability of the ground state of the final reaction product and not by compound I itself.

  DOI：

  10.1021/ic3006597
• 作为产物：
  描述：

  5,10,15,20-tetra(2',4',6'-trimethylphenyl)porphyrinatoiron(III) chloride 在 臭氧 作用下， 以 二氯甲烷-D2 为溶剂， 生成 chlorido(5,10,15,20-tetramesitylporphyrinato(1-))oxoiron(IV)
  参考文献：
  名称：

  Gross, Zeev; Nimri, Shay, Inorganic Chemistry, 1994, vol. 33, # 9, p. 1731 - 1732

  摘要：

  DOI：
• 作为试剂：
  描述：

  丁烷 在 chlorido(5,10,15,20-tetramesitylporphyrinato(1-))oxoiron(IV) 作用下， 以23%的产率得到丁酮
  参考文献：
  名称：

  在氟化碳溶剂中通过氧化铁-铁（IV）卟啉π-自由基阳离子络合物直接观察到CH键的氧化

  摘要：

  氧化铁（IV）卟啉π自由基阳离子物种参与各种含血红素的酶，并具有由高价铁中心和π共轭大环配体组成的特征性氧化态。然而，该复合物的短寿命阻碍了详细的反应性研究。本文报道的是通过以下方法制备的Fe IV（TMP +。）（O）（Cl）（2 ; TMP = 5,10,15,20-四甲基卟啉二价铁）的寿命（在10°C下80 s）显着增加。 α，α，α-三氟甲苯（TFT）中臭氧对Fe III（TMP）（Cl）（1）的氧化作用。与迄今报道的目前最稳定的物种相比，其寿命要长720倍。寿命的增加提高了反应的效率2朝向惰性烷烃底物，并直接观察2与伯C H键（BDE C H =约100 kcal mol -1）的反应。还获得了环己烷羟基化的活化参数。

  DOI：

  10.1002/anie.201901608

文献信息

• Spectroscopic Evidence for Acid-Catalyzed Disproportionation Reaction of Oxoiron(IV) Porphyrin to Oxoiron(IV) Porphyrin π-Cation Radical and Iron(III) Porphyrin
  作者：Kana Nishikawa、Yuki Honda、Hiroshi Fujii

  DOI：10.1021/jacs.9b13503

  日期：2020.3.18

  The disproportionation reaction of oxoiron(IV) porphyrin complex (II) to oxoiron(IV) porphyrin π-cation radical complex (I) and iron(III) porphyrin complex (III) have been proposed in various reactions. However, there have been no report that clarifies the disproportionation reaction spectroscopically. Here, we show direct evidence for the disproportionation reaction of II with absorption, 2H NMR,

  已在各种反应中提出了氧代铁 (IV) 卟啉复合物 (II) 向氧代铁 (IV) 卟啉 π 阳离子自由基复合物 (I) 和铁 (III) 卟啉复合物 (III) 的歧化反应。但是，还没有通过光谱来阐明歧化反应的报道。在这里，我们展示了 II 与吸收、2H NMR 和 EPR 光谱的歧化反应的直接证据。用停流技术对歧化反应的动力学研究可以分析为质子浓度的二级反应和II 浓度的一级反应。这些结果使我们能够提出歧化反应的机制，包括向 II 的氧代配体顺序添加两个质子，然后氧化另一个 II 以提供 I 和 III。
• Seeing the Long-Sought Intermediate in the Reaction of Oxoiron(IV) Porphyrin Cation Radicals with Olefins
  作者：Zeev Gross、Shay Nimri

  DOI：10.1021/ja00135a023

  日期：1995.8