| 1415831-56-9

• CAS: 1415831-56-9
• 化学式: C₂₄H₂₀Cl₂NOPPt
• 分子量: 635.389
• InChiKey: ZMYTXMUYSZDUSX-YWCDJFPNSA-L

反应信息

• 作为产物：
  描述：

  dichloro( 1,5-cyclooctadiene)platinum(ll) 、 以 二氯甲烷 为溶剂， 反应 4.0h， 以72%的产率得到
  参考文献：
  名称：

  Synthesis, characterisation and in vitro evaluation of platinum(II) and gold(I) iminophosphine complexes for anticancer activity

  摘要：

  The reactions of iminophosphine ligands with [PtCl2(COD)], [PtCl2(DMSO)(2)], and [Au(tht)Cl] has been investigated. The new platinum(II) and gold(I) complexes were characterised using elemental analysis, electrospray ionisation-mass spectrometry (ESI-MS), NMR (H-1 and P-31) and IR spectroscopy and X-ray diffraction studies. In vitro cytotoxic study results show that platinum and gold complexes block the proliferation of WHCO1 and KYSE450 cell lines with an IC50 range of 2.16-9.47 mu M. (c) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.09.053