[Fe(CO)(N4Py)](2+) | 1309371-30-9

• 英文名称: [Fe(CO)(N4Py)](2+)
• CAS: 1309371-30-9
• 化学式: C₂₄H₂₁FeN₅O
• 分子量: 451.311
• InChiKey: HFQGGIMULDIRHZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  ammonium iron(II) sulfate hexahydrate 、 一氧化碳 、 N,N-bis(2-pyridylmethyl)-N-(bis-2-pyridylmethyl)amine 以 水 为溶剂， 生成 [Fe(CO)(N4Py)](2+)
  参考文献：
  名称：

  Synthesis, Characterization, and Reactivity of the Stable Iron Carbonyl Complex [Fe(CO)(N4Py)](ClO₄)₂: Photoactivated Carbon Monoxide Release, Growth Inhibitory Activity, and Peptide Ligation

  摘要：

  Photoactivated carbon monoxide (CO) release by the iron carbonyl complex [Fe-II(CO)(N4Py)](ClO4)(2) (1) is described. Compound 1 is a low-spin ferrous complex the is highly stable and soluble in aerobic aqueous solutions. CO release was studied by the substitution of MeCN for CO, which displays saturation kinetics, and by the transfer of CO to deoxymyoglobin, which is slow in the dark but fast upon irradiation with UV light (365 nm). Compound I is active against PC-3 prostate cancer cells and shows potent photoinduced cytotoxicity. In addition, the iron carbonyl complex was attached to a short peptide toward the goal of tissue or cell-specific delivery.

  DOI：

  10.1021/ic200676s