| 828923-62-2

• CAS: 828923-62-2
• 化学式: C₂₉H₃₀FeN₄O₅
• 分子量: 570.428
• InChiKey: DLRFWOXHXSBVKI-FAVHNTAZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  cyclopenta-1,3-diene;iron(2+);methyl (2S)-3-[4-(cyclopenta-1,3-dien-1-ylmethoxy)phenyl]-2-[[2-(5-methyl-2,4-dioxopyrimidin-1-yl)acetyl]-[2-(phenylmethoxycarbonylamino)ethyl]amino]propanoate 、 ammonium formate 在 catalyst: Pd-C 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 以80%的产率得到
  参考文献：
  名称：

  A new ferrocene conjugate of a tyrosine PNA monomer: synthesis and electrochemical properties

  摘要：

  A new chiral ferrocene-labelled tyrosine PNA monomer I has been synthesised in good yield in both racemic and enantiomerically pure forms. It is suitable for insertion in various positions of PNA oligomers, a possibility that has been preliminarily demonstrated by synthesising the dimer 16. Moreover, in view of possible applications to nucleic acid detection, a preliminary voltarnmetric investigation on the electrochemical activity of monomer 1 and its synthetic precursors has been carried out in DMF. It appears that, despite the bulkiness of the PNA monomer backbone, its insertion on the ferrocene group only moderately lowers the latter's diffusion coefficients and peak currents, thus affording voltammetric detection limits in the order of 10(-6)-10(-7) M (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2004.09.049