(1,5-cyclooctadiene)(1-diphenylphosphino-1-((S)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2-yloxy)-methane)rhodium(I) tetrafluoroborate | 1391633-43-4

• 英文名称: (1,5-cyclooctadiene)(1-diphenylphosphino-1-((S)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2-yloxy)-methane)rhodium(I) tetrafluoroborate
• CAS: 1391633-43-4
• 化学式: BF₄*C₄₁H₃₆O₃P₂Rh
• 分子量: 828.393
• InChiKey: YHXXRLUAYBCESN-ONEVTFJLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  (S)-4-[(diphenylphosphanyl)methoxy]-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4a']dinaphptalene 、 bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate 以 二氯甲烷 为溶剂， 以92%的产率得到(1,5-cyclooctadiene)(1-diphenylphosphino-1-((S)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2-yloxy)-methane)rhodium(I) tetrafluoroborate
  参考文献：
  名称：

  Phosphine–phosphite ligands: chelate ring size vs. activity and enantioselectivity relationships in asymmetric hydrogenation

  摘要：

  合成了一系列新型膦-亚磷酸酯配体P(C)nOP (n = 1-4)，并用于铑催化前手性烯烃的不对称氢化，以研究螯合环尺寸的影响。在衣康酸二甲酯的氢化中获得了优异的ee（高达97.5％），并且在（Z）-α-乙酰氨基肉桂酸甲酯的氢化中观察到随着配体主链长度的增加，活性和对映选择性增加。

  DOI：

  10.1039/c2dt30386h
• 作为试剂：
  描述：

  衣康酸二甲酯 在 (1,5-cyclooctadiene)(1-diphenylphosphino-1-((S)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2-yloxy)-methane)rhodium(I) tetrafluoroborate 、 氢气 作用下， 以 二氯甲烷 为溶剂， 20.0 ℃ 、400.01 kPa 条件下， 反应 24.0h， 以87%的产率得到
  参考文献：
  名称：

  Asymmetric hydrogenation reactions with Rh and Ru complexes bearing phosphine–phosphites with an oxymethylene backbone

  摘要：

  Phosphine-phosphites 3a and 3b, derived from diphenylhydroxymethyl phosphine have been prepared. From these ligands [Rh(COD)(3a)]BF4 5a and RuCl2(3b)[(S,S)-DPEN] 6b (DPEN = 1,2-diphenylethylenediamine) were synthesized and their structure determined by X-ray diffraction. Ligands 3 are characterized by a small bite angle of 83 degrees. In addition, 5a led to an active catalyst for the hydrogenation of olefins, giving enantioselectivities of up to 96% ee. Likewise, compound 6b showed good activity and enantioselectivity in the hydrogenation of N-1-phenyl ethylidene aniline and a completed reaction at S/C = 500 in 24 h with 83% ee. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2014.04.001