BEt3-MeOH | 116123-33-2

• 英文名称: BEt3-MeOH
• CAS: 116123-33-2
• 化学式: C₇H₁₉BO
• 分子量: 130.038
• InChiKey: ICCDYKVNFFQZGU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  甲醇 、 三乙基硼 以 氘代苯 为溶剂， 生成 BEt3-MeOH
  参考文献：
  名称：

  Role of Equilibrium Associations on the Hydrogen Atom Transfer from the Triethylborane–Methanol Complex

  摘要：

  The triethylborane-methanol system used in radical deoxygenation and dehalogenation processes has been investigated. Unambiguous evidence for the formation of a complex between triethylborane and methanol is provided. It was shown that the complexation process is exothermic (Delta H-o approximate to -7.6 kcal mol(-1)) while being entropically disfavored (Delta S-o approximate to -24 cal mol(-1) K-1). This study demonstrates that only very small quantities of complex (1-2%) are present in most of the reported conditions used in dehalogenation and deoxygenation processes. Recalculating the rate constant for the hydrogen transfer to a secondary alkyl radical with this concentration suggests a value in the 10(6) M-1 s(-1) range for the complex itself, indicating a much more important activation of the O-H bond than previously thought. The importance of solvent effects is also highlighted. The formation of a larger amount of complex by the addition of methanol is accompanied by its deactivation via hydrogen bonding. These observations open new opportunitites for the future preparation of more effective hydrogen atom donors involving borane complexes.

  DOI：

  10.1021/jo302576c
• 作为试剂：
  描述：

  3-苄氧基-1-丙醇 在 sodium tetrahydroborate 、 正丁基锂 、 BEt3-MeOH 、 sodium hydride 、 pyridinium chlorochromate 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 28.0h， 生成
  参考文献：
  名称：

  Chiral polypropionate subunit by a chemoenzymatic approach

  摘要：

  Enzymatic desymmetrization of meso-4-methyl-3,5-syn-dioxolan-1,3,5,7-tetrol was found to be highly enantioselective leading to both acetylated enantiomers with high enantiomeric excess. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(98)00256-0