| 1616734-32-7

• CAS: 1616734-32-7
• 化学式: C₂₄H₂₂Cl₂NPPd
• 分子量: 532.745
• InChiKey: MGJJMJGVMRQYGX-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  2-溴苯胺 在 正丁基锂 、 硫酸 作用下， 以 四氢呋喃 、 乙醇 、 二氯甲烷 为溶剂， 反应 25.83h， 生成
  参考文献：
  名称：

  A “Hemilabile” Palladium–Carbon Bond: Characterization and Its Implication in Catalysis

  摘要：

  An unusual palladium carbon bond was identified in the crystal structure of a Pd(II) complex (VI) derived from 1-(2-diphenylphosphinophenyl)-2,5-dimethyl-1H-pyrrole (LA). Theoretical calculations indicate that the Pd C bond is covalent in nature. The complex exhibits fluxional behavior in solution at ambient temperature the Pd binds alternately to C2 and CS of pyrrole, generating equivalent, enantiomeric structures. Theory predicts that the transition state of this interconversion probably occurs through an unsaturated 14e complex, where the ligand binds the metal in a monodentate fashion. Comparison with related structures reported earlier has been made, and the possible implication of such unusual bonding in the context of catalysis of coupling reactions is discussed.

  DOI：

  10.1021/om5005435

文献信息

• Steric vis-à-vis electronic influence of phosphines on biaryl motif: Ligand design for coupling reactions with Chloroarenes
  作者：Debajyoti Saha、Raju Ghosh、Ranjan Dutta、Achintya Kumar Mandal、Amitabha Sarkar

  DOI：10.1016/j.jorganchem.2014.11.008

  日期：2015.1

  In order to assess relative contribution of steric factors and electron-richness of phosphine ligands on biaryl-type scaffolds, a set of 1-aryl-pyrazole/pyrrole derived ligands L1-L6 featuring either aryldicyclohexylphosphino or aryldiphenylphosphino donor group was synthesized. A bidentate coordination mode of ligands L1 or L2 was evident from a representative crystal structure that implied a possible hemilabile participation to facilitate catalytic steps. With N-arylpyrroles (L3-L5), where the second nitrogen donor on the heterocycle is absent, coupling reactions of unactivated chloroarenes still proceeded with comparable efficiency. Thus, suitably endowed triarylphosphines were found to be as efficient as more expensive aryldialkylphosphine analogs in reactions with chloroarenes, extending the scope of ligand design. (C) 2014 Elsevier B.V. All rights reserved.