acetic acid 5-(2,4-difluorophenyl)-2-(ethoxythiocarbonylsulfanyl)-5-oxopentyl ester | 1082074-75-6

• 英文名称: acetic acid 5-(2,4-difluorophenyl)-2-(ethoxythiocarbonylsulfanyl)-5-oxopentyl ester
• CAS: 1082074-75-6
• 化学式: C₁₆H₁₈F₂O₄S₂
• 分子量: 376.445
• InChiKey: QPTASKNFDMGKOG-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  acetic acid 5-(2,4-difluorophenyl)-2-(ethoxythiocarbonylsulfanyl)-5-oxopentyl ester 在 potassium carbonate 作用下， 以 乙腈 、 叔丁醇 为溶剂， 反应 2.0h， 以44%的产率得到2-ethoxy-7-fluoro-3-thiiranylmethyl-thiochromen-4-one
  参考文献：
  名称：

  A divergent approach to highly substituted benzothiepinones and to 2,3-dihydrothieno[2,3-b]thiopyran-4-ones

  摘要：

  The radical addition-transfer of S-(2-fluoro-phenacyl)xanthates can be used to construct rapidly benzothiepinones, including libraries of complex aza-bridged derivatives, and highly functionalized 2,3-dihydrothieno[2,3-b]thiopyran-4-ones. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.06.006
• 作为产物：
  描述：

  乙酸烯丙酯 、 dithiocarbonic acid S-[2-(2,4-difluoro-phenyl)-2-oxo-ethyl] ester O-ethyl ester 在 过氧化双月桂酰 作用下， 以 环己烷 为溶剂， 以71%的产率得到acetic acid 5-(2,4-difluorophenyl)-2-(ethoxythiocarbonylsulfanyl)-5-oxopentyl ester
  参考文献：
  名称：

  A divergent approach to highly substituted benzothiepinones and to 2,3-dihydrothieno[2,3-b]thiopyran-4-ones

  摘要：

  The radical addition-transfer of S-(2-fluoro-phenacyl)xanthates can be used to construct rapidly benzothiepinones, including libraries of complex aza-bridged derivatives, and highly functionalized 2,3-dihydrothieno[2,3-b]thiopyran-4-ones. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.06.006