dichloro[(M)-6,6'-dimethyl-α,α,α',α'-tetraphenyl[1,1'-biphenyl]-2,2'-dimethanolato(2-)-κO,κO']titanium | 461389-06-0

• 英文名称: dichloro[(M)-6,6'-dimethyl-α,α,α',α'-tetraphenyl[1,1'-biphenyl]-2,2'-dimethanolato(2-)-κO,κO']titanium
• CAS: 461389-06-0
• 化学式: C₄₀H₃₂Cl₂O₂Ti
• 分子量: 663.479
• InChiKey: RAZJKKUSISDGDP-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  二异丙氧基二氯化钛 、 [2'-(Hydroxy-diphenyl-methyl)-6,6'-dimethyl-biphenyl-2-yl]-diphenyl-methanol 在 2,6-di(tert-butyl)pyridine 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 生成 dichloro[(M)-6,6'-dimethyl-α,α,α',α'-tetraphenyl[1,1'-biphenyl]-2,2'-dimethanolato(2-)-κO,κO']titanium
  参考文献：
  名称：

  TitaniumLewis Acids for Asymmetric Catalysis: Synthesis and Structural Characterization of Dichloro[diolato(2−)-κO,κO′]bis(solvent)titanium ([TiCl2(diolato)(solvent)2]) Complexes

  摘要：

  The complexes [TiCl2{(R,R)-TADDOLato}(DME)](MeCN)-Me-. (3), and [TiCl2{(R,R)-1-Nph-TADDOL-ato}(McCN)(2)](CH2Cl2)-C-. (4b) (DME 1,2-dimethoxyethane; (R,R)-TADDOLato = (4R,5R)-2,2-dimethyl-a,a,a',a'-tetraphenyl-1,3-dioxotane-4,5-dimethanolato(2 (2-)-kappaO,kappaO'; (R,R)-1-Nph-TADDOLato = (4R,5R)2,2-dimethyl-a,a,a',a'-tetra(naphthalen-1-yl)-1,3-dioxotane-4,5-dimethanolato(2-)-kappaO,kappaO') were prepared and isolated in high yield as stable crystalline materials (Scheme 1). They constitute ideally suited and easy-to-handle catalyst precursors for a large number of Ti-catalyzed asymmetric reactions, for which they have been previously generated in situ. The X-ray crystal structures of 3 and 4b show a distorted octahedral geometry around Ti with the chloro ligands in mutual trans positions (Figs. 5 and 6). The new chiral diols a-(1S,3R)-3-hydroxy-2,2,3-trimethylcyclopentyl]-a-phenylbenzenemethanol (13a), derived from camphoric acid (5), and (M) -6,6'-dimethyl-a,a,a',a'-tetraphenyl[1,1'-biphenyl]-2,2'-dimethanol (15) were prepared (Schemes 3 and 4). These new ligands are able to form mononuclear complexes with the (TiCl2)-Cl-IV, fragment. The corresponding complex 14 derived front 13a was characterized by X-ray as a mixed THF/MeCN adduct.

  DOI：

  10.1002/1522-2675(200206)85:6<1597::aid-hlca1597>3.0.co;2-n