[3-(2-(acetamido-C(2))acetamido)-2,2,5,5-tetramethylpyrrolidinyl-N-oxyl](2,2'-bipyridine)bromodimethylplatinum(IV) | 165269-50-1

• 英文名称: [3-(2-(acetamido-C(2))acetamido)-2,2,5,5-tetramethylpyrrolidinyl-N-oxyl](2,2'-bipyridine)bromodimethylplatinum(IV)
• CAS: 165269-50-1；165522-63-4
• 化学式: C₂₄H₃₅BrN₅O₃Pt
• 分子量: 716.558
• InChiKey: YQFGJEQXVFNALL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  dimethyl(2,2'-bipyridine)platinum(II) 、 3-2-(2-溴乙酰氨基)乙酰胺]-2,2,5,5-四甲基-1-吡咯烷基氧化物 以 丙酮 为溶剂， 以87%的产率得到[3-(2-(acetamido-C(2))acetamido)-2,2,5,5-tetramethylpyrrolidinyl-N-oxyl](2,2'-bipyridine)bromodimethylplatinum(IV)
  参考文献：
  名称：

  Stable Organoplatinum(IV) Complexes with Pendant Free Radicals

  摘要：

  Oxidative addition of 2-bromoacetamido derivatives of the stable, free-radical nitroxides tempo and proxyl (2,2,6,6-tetramethylpiperidinyl-N-oxyl and 2,2,5,5-tetramethylpyrrolidinyl-N-oxyl, respectively) to [PtMe(2)(bpy)] (bpy = 2,2(')-bipyridine) affords the novel organoplatinum-(IV) complexes [Pt{CH2C(O)NH-tempo}BrMe(2)(bpy)] (1), [Pt{CH2C(O)NH-proxyl}BrMe(2)(bpy)] (2), [Pt{CH2C(O)NHCH2-proxyl}BrMe(2)(bpy)] (3), [Pt{CH2C(O)NHCH2C(O)NH-proxyl}-BrMe(2)(bpy)] (4), and [Pt{CH2C(O)NH(CH2)(3) NHC(O)-proxyl}BrMe(2)(bpy)] (5) in good yields. The complexes exist as a mixture of trans (a) and cis (b) isomers and are the result of traits and cis oxidative addition, respectively. The broad H-1 NMR spectra and distinctive three-line pattern in the ESR spectra conclusively demonstrate the paramagnetic nature of the complexes. The X-ray structure of la was determined. Crystals of la are monoclinic, space group P2(1)/c, with a = 13.401(2) Angstrom, b = 16.979(1) Angstrom, c = 11.199(1) Angstrom, beta = 93.01(1)degrees, Z = 4, and R = 0.0499. The bromo and Pt-C sigma-bonded 4-(2-acetamido)-tempo ligands occupy a mutually trans arrangement about the octahedral platinum(IV) center. Complexes 1-5 are rare examples of stable organometallic species with pendant free radicals.

  DOI：

  10.1021/om00005a019