2-[dimetyl(octyl)ammonio]ethyl octylphosphonate | 1616596-39-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: 2-[dimetyl(octyl)ammonio]ethyl octylphosphonate
• CAS: 1616596-39-4
• 化学式: C₂₀H₄₄NO₃P
• 分子量: 377.548
• InChiKey: OVFDXPNMFIFBRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.35
• 重原子数：
  25.0
• 可旋转键数：
  18.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.36
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  对甲苯磺酸正辛酯 在 吡啶 作用下， 以 乙腈 为溶剂， 反应 27.0h， 生成 2-[dimetyl(octyl)ammonio]ethyl octylphosphonate
  参考文献：
  名称：

  Novel fluorinated dialkylphosphonatocholines: Synthesis, physicochemical properties and antiprotozoal activities against Acanthamoeba spp.

  摘要：

  The synthesis of four new organophosphorous gemini surfactants is presented. They belong to the class of dialkylphosphonatocholines. Tails are represented with two octyl groups both non or partially fluorinated. The synthesis was performed by reaction of alkylphosphonic acids with choline derivatives in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride. The micellar, surface active, and solubilization properties of new surfactants were studied. Antiprotozoal activities were tested against Acanthamoeba lugdunensis and Acanthamoeba quina. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2014.04.008