| 1071436-98-0

• CAS: 1071436-98-0
• 化学式: C₁₀H₁₈B₁₀
• 分子量: 246.363
• InChiKey: IGZOAGGDHOYZIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  在 三乙烯二胺 、 potassium osmate(VI) dihydrate 、 甲基磺酰胺 、 potassium carbonate 、 potassium hexacyanoferrate(III) 、 sodium hydrogensulfite 作用下， 以 水 、 丙酮 为溶剂， 生成 2-o-carboranephenylethylene glycol
  参考文献：
  名称：

  CN115557982

  摘要：

  公开号：
• 作为产物：
  描述：

  在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 以263 mg的产率得到
  参考文献：
  名称：

  CN115557981

  摘要：

  公开号：

文献信息

• Transition Metal Catalyzed Direct Amination of the Cage B(4)–H Bond in <i>o</i>-Carboranes: Synthesis of Tertiary, Secondary, and Primary <i>o</i>-Carboranyl Amines
  作者：Hairong Lyu、Yangjian Quan、Zuowei Xie

  DOI：10.1021/jacs.6b07086

  日期：2016.10.5

  catalyzed regioselective amination of the cage B(4)-H bond in o-carboranes has been achieved for the first time using O-benzoyl hydroxylamines or organic azides as the amination reagents, leading to the preparation of a series of tertiary and secondary carboranyl amines. Both amination reactions proceeded under mild conditions without the addition of any external oxidants. Hydrogenolysis of the resultant

  使用邻苯甲酰羟胺或有机叠氮化物作为胺化试剂，首次实现了过渡金属催化的邻碳硼烷中笼型 B(4)-H 键的区域选择性胺化，从而制备了一系列叔、仲羰基胺。两种胺化反应均在温和条件下进行，无需添加任何外部氧化剂。所得产物4-N(CH2Ph)2-o-碳硼烷的氢解以定量产率提供伯碳硼烷胺，4-氨基-o-碳硼烷。
• Three-Component [2+2+2] Cycloaddition of Carboryne, Unactivated Alkene, and Alkyne via Zirconacyclopentane Mediated by Nickel: One-Pot Synthesis of Dihydrobenzocarboranes
  作者：Shikuo Ren、Zaozao Qiu、Zuowei Xie

  DOI：10.1002/anie.201106212

  日期：2012.1.23

  of a transition‐metal center to an olefin or alkyne can significantly modify its reactivity, which makes the selective coupling of different alkenes or alkynes to carboryne possible. An example of a three‐component [2+2+2] cycloaddition reaction of carboryne with unactivated alkene (see scheme, blue) and alkyne (red) mediated by zirconium and nickel complexes is described.

  混合三（合一）：过渡金属中心与烯烃或炔烃的络合可显着改变其反应活性，这使得不同烯烃或炔烃与碳硼烷的选择性偶联成为可能。举例说明了碳炔与锆和镍络合物介导的未活化烯烃（见方案，蓝色）和炔烃（红色）的三组分[2 + 2 + 2]环加成反应的一个例子。
• Rhodium‐Catalyzed Regioselective Hydroxylation of Cage B−H Bonds of <i>o</i> ‐Carboranes with O ₂ or Air
  作者：Hairong Lyu、Yangjian Quan、Zuowei Xie

  DOI：10.1002/anie.201605880

  日期：2016.9.19

  A rhodium‐catalyzed hydroxylation of a cage B4−H bond in o‐carboranes with either O2 or air as the oxygen source is described, and serves as a new methodology for the regioselective generation of a series of 4‐OH‐o‐carboranes in a one‐pot process. The use of either O2 or air as both the oxidant and the oxygen source makes this protocol very environmentally friendly and practical.

  描述了以O 2或空气为氧源的邻氨基甲酸酯中笼形B4-H键的铑催化羟基化反应，它是一种用于区域选择性生成一系列4-OH- o-碳氮烷的新方法在一个锅的过程中。使用O 2或空气作为氧化剂和氧气源使该协议非常环保且实用。
• Light-enabled alkenylation of iodocarboranes with unactivated alkenes
  作者：Hangcheng Ni、Zhenpin Lu、Zuowei Xie

  DOI：10.1039/d1dt03726a

  日期：——

  The synthesis of alkenylated-o-carboranes via photoalkenylation of iodocarboranes with unactivated alkenes has been achieved. This strategy features a transition metal-free protocol, a light-promoted reaction under mild reaction conditions, broad substrate scope and good functional group tolerance. Control experiments suggest that the reaction may involve the cage C-centered radical species.

  alkenylated-的合成ö -carboranes经由与未活化的烯烃iodocarboranes的photoalkenylation已经实现。该策略具有无过渡金属方案、温和反应条件下的光促进反应、广泛的底物范围和良好的官能团耐受性。对照实验表明该反应可能涉及笼 C 中心自由基物种。
• Transition-Metal-Mediated Three-Component Cascade Cyclization: Selective Cage B–C(sp²) Coupling of Carborane with Aromatics and Synthesis of Carborane-Fused Tricyclics
  作者：Yangjian Quan、Zaozao Qiu、Zuowei Xie

  DOI：10.1021/ja503489b

  日期：2014.5.28

  Zirconium/nickel comediated one-pot three-component cascade cyclization of carboryne, alkene, and 2-bromophenyltrimethylsilylacetylene has been achieved, leading to the formation of a series of C,C,B-substituted carborane-fused tricyclics. On the basis of experimental results, a plausible mechanism is proposed including [2 + 2 + 1] cross-cyclotrimerization followed by intramolecular direct selective cage B-C(sp(2)) coupling. This represents the first example of direct cage B-C(phenyl) coupling via cage B-H activation.