[2,6-bis(4,4-dimethyl-2-oxazolinyl)phenyl]chloropalladium | 945657-56-7

• 英文名称: [2,6-bis(4,4-dimethyl-2-oxazolinyl)phenyl]chloropalladium
• 英文别名: [PdCl(2,6-bis(oxazolinyl)phenyl)]
• CAS: 945657-56-7
• 化学式: C₁₆H₁₉ClN₂O₂Pd
• 分子量: 413.212
• InChiKey: YBGNHQYZCCNTNK-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  trans-bromo(2,6-dicarboxyphenyl)bis(triphenylphosphine)palladium 、 2-氨基-2-甲基-1-丙醇 在 草酰氯 、 甲基磺酰氯 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 以48%的产率得到[2,6-bis(4,4-dimethyl-2-oxazolinyl)phenyl]chloropalladium
  参考文献：
  名称：

  Synthesis of [2,6-Bis(2-oxazolinyl)phenyl]palladium Complexes via the Ligand Introduction Route

  摘要：

  A series of [2,6-bis(2-oxazolinyl)phenyl]palladium (Phebox-Pd) complexes were synthesized via the ligand introduction route. trans-Bromo(2,6-dicarboxyphenyl)bis(triphenylphosphine)palladium was prepared by the reaction of 2-bromoisophthalic acid with Pd(PPh3)(4) in 93% yield, and the carboxy groups of the palladium complex were converted into oxazolinyl groups to give the Phebox-Pd complexes in 44-57% yield.

  DOI：

  10.1021/om800666x

文献信息

• A new, easily recyclable arylating agent based on a diphosphino-digold(i) complex
  作者：Marianne Stol、Dennis J. M. Snelders、Huub Kooijman、Anthony L. Spek、Gerard P. M. van Klink、Gerard van Koten

  DOI：10.1039/b701271c

  日期：——

  The synthesis of two organogold(I) complexes, [(Au(NCN))2(dppbp)] (6) and [(Au(Phebox))2(dppbp)] (9), and their application in subsequent transmetalating reactions are described. A trinuclear organogold(I) complex, [(AuCl)3(tdpppb)] (4) is also reported, which exhibits a surprisingly high solubility in dichloromethane. It was found that 6 and 9 can cleanly transfer the anionic NCN-([C6H3(CH2NMe2)2-2,6]−) or Phebox-([2,6-bis(oxazolinyl)phenyl]−) moiety to TiIV and PdII centers, respectively. The coproduct [(AuCl)2(dppbp)] (3, dppbp is [4-Ph2PC6H4]2 (1)) formed during this transmetalation reaction, precipitates almost quantitatively from the reaction mixture (toluene) and can thus be separated by simple filtration. In comparison, [AuCl(PPh3)], formed as the coproduct in the transmetalation reaction of [Au(NCN)(PPh3)] with metal salts, has a higher solubility in apolar solvents and thus is more difficult to separate from the resultant organometallic complex. Digold complex 6 has been characterized by NMR spectroscopy and crystallographic analyses. These analyses show that the two gold units are essentially independent. The formation of a dimetallic transmetalating agent based on gold(I) had no effect on its transmetalating properties.

  本文介绍了两种有机金（I）配合物 [(Au(NCN))2(dppbp)] (6) 和 [(Au(Phebox))2(dppbp)] (9) 的合成及其在随后的反金属化反应中的应用。报告还介绍了一种三核有机金（I）配合物[(AuCl)3(tdpppb)] (4)，它在二氯甲烷中的溶解度之高令人惊讶。研究发现，6 和 9 可以分别将阴离子 NCN-（[C6H3(CH2NMe2)2-2,6]-）或 Phebox-（[2,6-双（恶唑啉基）苯基]-）分子干净地转移到 TiIV 和 PdII 中心。在这一跨金属化反应中形成的副产物[(AuCl)2(dppbp)]（3，dppbp 为 [4-Ph2PC6H4]2 (1)）几乎定量地从反应混合物（甲苯）中析出，因此只需简单过滤即可分离。相比之下，在[Au(NCN)(PPh3)]与金属盐的反金属反应中形成的副产物[AuCl(PPh3)]在非极性溶剂中的溶解度较高，因此更难从生成的有机金属复合物中分离出来。Digold 复合物 6 已通过核磁共振光谱和晶体学分析进行了表征。这些分析表明，两个金单元基本上是独立的。以金（I）为基础形成的二金属透金属剂对其透金属特性没有影响。