[Ru(tpy)(bipyz)Cl]PF6 | 161302-02-9

• 英文名称: [Ru(tpy)(bipyz)Cl]PF6
• 英文别名: [RuCl(2,2':6',2''-terpyridine)(2,2'-bipyrazine)](hexafluorophosphate)；[RuCl(tpy)(bpz)]PF6
• CAS: 161302-02-9
• 化学式: C₂₃H₁₇ClN₇Ru*F₆P
• 分子量: 672.922
• InChiKey: BTUVKWGILJBYPC-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  silver perchlorate 、 [Ru(tpy)(bipyz)Cl]PF6 在 water 作用下， 以 水 、 丙酮 为溶剂， 以90%的产率得到[Ru(2,2',2''-terpyridine)(2,2'-bipyrazine)(H2O)](ClO4)2
  参考文献：
  名称：

  Gerli, Alessandra; Reedijk, Jan; Lakin, Miles T., Inorganic Chemistry, 1995, vol. 34, # 7, p. 1836 - 1843

  摘要：

  DOI：
• 作为产物：
  描述：

  ammonium hexafluorophosphate 、 Ru(tpy)(Cl)₃ 、 2,2'-联吡嗪 在 triethyl amine 、 lithium chloride 作用下， 以 乙醇 、 水 为溶剂， 以20%的产率得到[Ru(tpy)(bipyz)Cl]PF6
  参考文献：
  名称：

  Gerli, Alessandra; Reedijk, Jan; Lakin, Miles T., Inorganic Chemistry, 1995, vol. 34, # 7, p. 1836 - 1843

  摘要：

  DOI：

文献信息

• Toward Optimal Ru(II) Photocages: Balancing Photochemistry, Stability, and Biocompatibility Through Fine Tuning of Steric, Electronic, and Physiochemical Features
  作者：Dmytro Havrylyuk、Kimberly Stevens、Sean Parkin、Edith C. Glazer

  DOI：10.1021/acs.inorgchem.9b02065

  日期：2020.1.21

  Ru(II) complex photocages are used in a variety of biological applications, but the thermal stability, photosubstitution quantum yield, and biological compatibility of the most commonly used Ru(II) systems remain unoptimized. Here, multiple compounds used in photocaging applications were analyzed and found to have several unsatisfactory characteristics. To address these deficiencies, three new scaffolds were designed to improve key properties through modulation of a combination of electronic, steric, and physiochemical features. One of these new systems, containing the 2,2'-biquinoline-4,4'-dicarboxylic acid (2,2'-bicinchoninic acid) ligand, fulfills several of the requirements for an optimal photocage. Another complex, containing the 2-benzothiazol-2-yl-quinoline ligand, provides a scaffold for the creation of "dual action" agents.