(2-(4'-methoxy[4]helicen-1'-yl)pyridinato-(N,C2'))(dimethylsulfoxide-S)platinum(II)chloride | 1272661-80-9

• 英文名称: (2-(4'-methoxy[4]helicen-1'-yl)pyridinato-(N,C2'))(dimethylsulfoxide-S)platinum(II)chloride
• 英文别名: (M)-[H₆Pt(dmso)Cl]
• CAS: 1272661-80-9；1273498-78-4；1273493-91-6
• 化学式: C₂₆H₂₂ClNO₂PtS
• 分子量: 643.065
• InChiKey: NVJZVVOKKWBZIY-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (2-(4'-methoxy[4]helicen-1'-yl)pyridinato-(N,C2'))(dimethylsulfoxide-S)platinum(II)chloride 、 silver benzoate 以 丙酮 为溶剂， 以40%的产率得到
  参考文献：
  名称：

  From Hetero- to Homochiral Bis(metallahelicene)s Based on a Pt^III−Pt^III Bonded Scaffold: Isomerization, Structure, and Chiroptical Properties

  摘要：

  Hetero- and homochiral diastereomeric bis(metallahelicene)s have been synthesized. They possess a rare Pt-III-Pt-III scaffold bridged by benzoato ligands. It is shown that heterochiral (P,M)-bis(Pt-III-[6]helicene) can isomerize into the homochiral (P,P)- and (M,M)-bis-(Pt-III-[6]helicene). A theoretical study shows a unique sigma-pi conjugation between the two pi-helices and the sigma-Pt-III-Pt-III scaffold that impacts the strong chiroptical properties.

  DOI：

  10.1021/ja200129y
• 作为产物：
  描述：

  dichlorobis(dimethyl sulfoxide)platinum(II) 、 2-(4-methoxy[4]helicen-1-yl)pyridine 以 甲苯 为溶剂， 以85%的产率得到(2-(4'-methoxy[4]helicen-1'-yl)pyridinato-(N,C2'))(dimethylsulfoxide-S)platinum(II)chloride
  参考文献：
  名称：

  From Hetero- to Homochiral Bis(metallahelicene)s Based on a Pt^III−Pt^III Bonded Scaffold: Isomerization, Structure, and Chiroptical Properties

  摘要：

  Hetero- and homochiral diastereomeric bis(metallahelicene)s have been synthesized. They possess a rare Pt-III-Pt-III scaffold bridged by benzoato ligands. It is shown that heterochiral (P,M)-bis(Pt-III-[6]helicene) can isomerize into the homochiral (P,P)- and (M,M)-bis-(Pt-III-[6]helicene). A theoretical study shows a unique sigma-pi conjugation between the two pi-helices and the sigma-Pt-III-Pt-III scaffold that impacts the strong chiroptical properties.

  DOI：

  10.1021/ja200129y

文献信息

• Diastereo‐ and Enantioselective Synthesis of Organometallic Bis(helicene)s by a Combination of CH Activation and Dynamic Isomerization
  作者：Chengshuo Shen、Emmanuel Anger、Monika Srebro、Nicolas Vanthuyne、Loïc Toupet、Christian Roussel、Jochen Autschbach、Régis Réau、Jeanne Crassous

  DOI：10.1002/chem.201302479

  日期：2013.12.2

  Homochiral and heterochiral cis‐bis‐cycloplatinated‐[6]helicene derivatives 1 b1, 2, as representative examples of platina[6]helicenes that share a common platinum center, have been prepared. A diastereo‐ and enantioselective synthesis, which combines CH activation and dynamic isomerization from heterochiral structure 1 b2 into homochiral structure 1 b1, is also described. Overall, this isomerization

  制备了手性和杂手性的顺式-双-环-环化-[6]螺旋衍生物1 b 1，2，它们是具有共同铂中心的铂[6]螺旋烯的代表性实例。甲diastereo-和对映选择性合成，它结合了CH活化和动态异构化从异向结构1b的2成纯手性结构1b中1，也被描述。总的来说，这种异构化过程导致手性信息从一个螺旋烯部分转移到另一个螺旋烯部分。同手性（P）‐和（M）‐ 1 b 1的手性被氧化成相应的（P）-和（M）-二碘-Pt IV配合物后被大大修饰（5）。通过执行理论计算也分析了这些变化。Ç  ħ活化有机金属helicenes的合成通过的制备进一步说明顺式-双cycloplatinated- [8]螺烯1c中。