名称:
The different behaviour of the di-2-pyridylketone 2-thenoylhydrazone in two organotin compounds. Synthesis, X-ray structure and biological activity
摘要:
Two organotin compounds [SnPh(dpt)Cl-2] (1) and [SnPh(3)Cl(OH2)].Hdpt (2) (Hdpt = di-2-pyridylketone 2-thenoylhydrazone) have been synthesized and characterized by IR spectroscopy and X-ray diffraction. Hdpt behaves differently in the two compounds: it is deprotonated and ONN tridentate in 1 and uncoordinated in 2, where pairs of hydrogen-bonded [SnPh(3)Cl(OH2)] and Hdpt molecules are present. The tin environment is octahedral in 1 and trigonal bipyramidal in 2. Compound 2 has shown good antimicrobial activity against Gram-positive bacteria and moulds in vitro. Neither compound showed genotoxic properties.
DOI:
10.1016/0022-328x(94)00003-u