4-[1,1-Bis[3,5-bis(diethylaminomethyl)-4-hydroxyphenyl]ethyl]-2,6-bis(diethylaminomethyl)phenol | 1086840-21-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-[1,1-Bis[3,5-bis(diethylaminomethyl)-4-hydroxyphenyl]ethyl]-2,6-bis(diethylaminomethyl)phenol
• CAS: 1086840-21-2
• 化学式: C₅₀H₈₄N₆O₃
• 分子量: 817.255
• InChiKey: WHLRIEOJOFXYCS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  59
• 可旋转键数：
  27
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  80.1
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• TRI-ARYL COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME
  申请人：Priel Esther

  公开号：US20100256382A1

  公开（公告）日：2010-10-07

  The present invention relates to a novel class of tri-aryl compounds, compositions comprising the same and processes for the preparation thereof.
• TELOMERASE ACTIVATING COMPOUNDS AND METHODS OF USE THEREOF
  申请人：Gazit Aviv

  公开号：US20100267667A1

  公开（公告）日：2010-10-21

  The present invention is directed to use of a series of compounds and compositions comprising the same for activating telomerase and treating diseases, disorders and/or conditions related thereto.
• Compounds for the Treatment of Diabetes and Disease Complications Arising from Same
  申请人：BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY

  公开号：US20160263124A1

  公开（公告）日：2016-09-15

  The present invention is directed to use of a series of tri-aryl compounds and compositions comprising the same for the treatment of diabetes and disease conditions arising as a consequence of the same.
• TELOMERASE ACTIVATING COMPOUNDS FOR USE IN FERTILITY AND RELATED APPLICATIONS
  申请人：BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY

  公开号：US20190350878A1

  公开（公告）日：2019-11-21

  The present invention is directed to methods and uses of a series of compounds and compositions comprising the same for treating diseases, disorders and/or conditions related to fertility and preserving same and conditions related to same. In some aspects, the compounds and or compositions as herein described promote, improve, recover or restore fertility in a subject in need thereof, including in male and/or female subjects. Such methods/uses include promoting, enhancing or improving fertility-associated cell or tissue yield as part of an in vitro fertilization protocol.
• US9663448B2
  申请人：——

  公开号：US9663448B2

  公开（公告）日：2017-05-30