2-methoxy-4-(2-pyridyl)-6-ferrocenyl-pyridine | 884597-99-3

• 英文名称: 2-methoxy-4-(2-pyridyl)-6-ferrocenyl-pyridine
• CAS: 884597-99-3
• 化学式: C₂₁H₁₈FeN₂O
• 分子量: 370.234
• InChiKey: BJFJSKCSHFEIRT-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1-ferrocenyl-3-(2-pyridinyl)prop-2-en-1-one 、 sodium methylate 、 丙二腈 以 甲醇 为溶剂， 以81%的产率得到2-methoxy-4-(2-pyridyl)-6-ferrocenyl-pyridine
  参考文献：
  名称：

  An efficient synthesis of ferrocenyl substituted 3-cyanopyridine derivatives under ultrasound irradiation

  摘要：

  An efficient synthesis of 2-alkoxy-4-aryl-6-ferrocenyl-3-cyanopyridines via the condensation of ferrocenyl substituted chalcones with malononitrile in a freshly prepared sodium alkoxide solution under ultrasound irradiation was investigated. Especially noteworthy, the reaction of 1-ferrocenyl-3-(pyridin-2-yl)prop-2-ene-1-one with malononitrile afforded 2-alkoxy-4-pyridyl-6-ferrocenylpyridine, with the loss of CN group on the 3-position of pyridine ring was first observed. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.09.046