magnesium;tert-butyl-[dimethyl(piperidin-1-ylmethyl)silyl]azanide | 1337982-35-0

• 英文名称: magnesium;tert-butyl-[dimethyl(piperidin-1-ylmethyl)silyl]azanide
• CAS: 1337982-35-0
• 化学式: C₂₄H₅₄MgN₄Si₂
• 分子量: 479.196
• InChiKey: RQJNWEJIVMRMSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  31
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  8.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  (tert-butylamino)(piperidinomethyl)dimethylsilane 在 二丁基镁 作用下， 以 正庚烷 为溶剂， 反应 20.0h， 以63%的产率得到magnesium;tert-butyl-[dimethyl(piperidin-1-ylmethyl)silyl]azanide
  参考文献：
  名称：

  Control of N- or C-Bridging Mode in Dimeric Butylmagnesium Silylamides

  摘要：

  The simple approach to cleave 4,S-dihydro-2-furyl with lithiated primary amines yields a wide range of N-alkyl-substituted (aminomethyl)silazanes. These are easily deprotonated by dibutylmagnesium, resulting in either magnesium disilylamides or butylmagnesium silylamides upon variation of the stochiometric ratios and reaction temperatures. The obtained dimeric butylmagnesium silylamide compounds [{(CH(3))(2)Si(CH(2)NC(5)H(10))(NR)}Mg(n-Bu)](2) (R = t-Bu,i-Pr), examined by single-crystal X-ray diffraction analysis, exhibit different bridging modes Mg-El-Mg (El = C, N) according to the steric demand of the ligand. This observation has been studied using theoretical methods.

  DOI：

  10.1021/om200587n