| 1436464-03-7

• CAS: 1436464-03-7
• 化学式: C₁₄H₂₁ClN₆OPt
• 分子量: 519.893
• InChiKey: YTKNKXPKLPOLPQ-UHFFFAOYSA-M

反应信息

• 作为反应物：
  描述：

  以 甲醇 、 硝基甲烷 、 氯仿 、 丙酮 为溶剂， 反应 2.17h， 生成
  参考文献：
  名称：

  Amidrazone Complexes from a Cascade Platinum(II)-Mediated Reaction between Amidoximes and Dialkylcyanamides

  摘要：

  The aryl amidoximes R'C6H4C(NH2)=NOH (R' = Me, 2a; H, 2b; CN, 2c; NO2, 2d) react with the dialkylcyanamide platinum(II) complexes trans-[PtCl2(NCNAlk(2))(2)] (Alk(2) = Me-2, 1a; C5H10, 1b) in a 1:1 molar ratio in CHCl3 to form chelated mono addition products [3a-h]Cl, viz. [PtCl-(NCNAlk(2)){(N) under barH=C(NR2)O (N) under bar =C(C6H4R')NH2}]Cl (Alk(2) = Me-2; R' = Me, a; H, b; CN, c; NO2, d; Alk(2) = C5H10; R' = Me, e; H, f; CN, g; NO2, h). In the solution, these species spontaneously transform to the amidrazone complexes [PtCl2{(N) under barH=C(NR2)NC(C6H4R')(N) under barH(2)}] (7a h; 36-47%); this conversion proceeds more selectively (49-60% after column chromatography) in the presence of the base (PhCH2)(3)N. The observed reactivity pattern is specific for NCNAlk(2) ligands, and it is not realized for conventional alkyl- and arylnitrile ligands. The mechanism of the cascade reaction was studied by trapping the isocyanate intermediates [PtCl(NCO){(N) under barH=C(NR2)NC(C6H4R')(N) under bar NH2}] (5a-h) and also by ESI-MS identification of the ammonia complexes [PtCl(NH3)(N) under barH=C(NR2)NC(C6H4R')(N) under bar NH2)](+) ([6a-h]) in solution. The complexes [3a]Cl, [3c-h]Cl, 5a-h and 7ah- were characterized by elemental analyses, high resolution ESI-MS, IR, and H-1 NMR, techniques, while 5b, 5d, 5g, 7b, and 7e were also studied using single crystal X-ray diffraction.

  DOI：

  10.1021/ic4000878
• 作为产物：
  描述：

  在 三苄胺 作用下， 以 氯仿 为溶剂， 反应 1.12h， 以58%的产率得到
  参考文献：
  名称：

  Amidrazone Complexes from a Cascade Platinum(II)-Mediated Reaction between Amidoximes and Dialkylcyanamides

  摘要：

  The aryl amidoximes R'C6H4C(NH2)=NOH (R' = Me, 2a; H, 2b; CN, 2c; NO2, 2d) react with the dialkylcyanamide platinum(II) complexes trans-[PtCl2(NCNAlk(2))(2)] (Alk(2) = Me-2, 1a; C5H10, 1b) in a 1:1 molar ratio in CHCl3 to form chelated mono addition products [3a-h]Cl, viz. [PtCl-(NCNAlk(2)){(N) under barH=C(NR2)O (N) under bar =C(C6H4R')NH2}]Cl (Alk(2) = Me-2; R' = Me, a; H, b; CN, c; NO2, d; Alk(2) = C5H10; R' = Me, e; H, f; CN, g; NO2, h). In the solution, these species spontaneously transform to the amidrazone complexes [PtCl2{(N) under barH=C(NR2)NC(C6H4R')(N) under barH(2)}] (7a h; 36-47%); this conversion proceeds more selectively (49-60% after column chromatography) in the presence of the base (PhCH2)(3)N. The observed reactivity pattern is specific for NCNAlk(2) ligands, and it is not realized for conventional alkyl- and arylnitrile ligands. The mechanism of the cascade reaction was studied by trapping the isocyanate intermediates [PtCl(NCO){(N) under barH=C(NR2)NC(C6H4R')(N) under bar NH2}] (5a-h) and also by ESI-MS identification of the ammonia complexes [PtCl(NH3)(N) under barH=C(NR2)NC(C6H4R')(N) under bar NH2)](+) ([6a-h]) in solution. The complexes [3a]Cl, [3c-h]Cl, 5a-h and 7ah- were characterized by elemental analyses, high resolution ESI-MS, IR, and H-1 NMR, techniques, while 5b, 5d, 5g, 7b, and 7e were also studied using single crystal X-ray diffraction.

  DOI：

  10.1021/ic4000878