(η5-C5H4COOCH2CH2OMe)2NbCl2 | 1441678-28-9

• 英文名称: (η5-C5H4COOCH2CH2OMe)2NbCl2
• CAS: 1441678-28-9
• 化学式: C₁₈H₂₂Cl₂NbO₆
• 分子量: 498.181
• InChiKey: GXJTXBZSKSBNDE-UHFFFAOYSA-L

反应信息

• 作为产物：
  描述：

  NbCl4*2THF 、 以 四氢呋喃 为溶剂， 以32%的产率得到(η5-C5H4COOCH2CH2OMe)2NbCl2
  参考文献：
  名称：

  Vanadocene and niobocene dihalides containing electron-withdrawing substituents in the cyclopentadienyl rings: Synthesis, characterization and cytotoxicity

  摘要：

  The first example of the group V metallocene dihalides substituted in the cyclopentadienyl rings with electron-withdrawing substituents is reported. This study includes synthesis and spectroscopic characterization of the series of vanadocene and niobocene compounds functionalized in the cyclopentadienyl rings with the ester groups. Structures of (eta(5)-C5H4COOPh)(2)VCl2, (eta(5)-C5H4COOMe)(2)VBr2 center dot CH2Cl2, (eta(5)-C5H4-COOPh)(2)NbCl2, (eta(5)-C5H4COOMe)(2)NbBr2 and (eta(5)-C5H4COOEt)(2)NbBr2 were determined by X-ray diffraction analysis. Cytotoxic activity toward human leukemia cells MOLT-4 was established in vitro for all newly prepared metallocene compounds. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2013.03.018