diammonium fumarate | 14548-85-7

• 英文名称: diammonium fumarate
• 英文别名: fumaric acid ammonium salt；ammonium fumarate；diammonium salt of fumaric acid；Ammonium hydrogen fumarate；azanium;(E)-4-hydroxy-4-oxobut-2-enoate
• CAS: 14548-85-7
• 化学式: C₄H₄O₄*2H₃N
• 分子量: 150.134
• InChiKey: NLVWBYNKMPGKRG-TYYBGVCCSA-N

物化性质

• 熔点：
  243-254 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -0.13
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  75.6
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  diammonium fumarate 在 enzyme aspartase 作用下， 以 重水 为溶剂， 生成 (2S,3S)-(2,3-(2)H2)天冬氨酸
  参考文献：
  名称：

  Assignment of the chemical shift values of N-trityl l-homoserine lactone

  摘要：

  DOI：

  10.1016/s0040-4039(00)80413-x
• 作为产物：
  描述：

  富马酸 在 ammonium hydroxide 作用下， 以 水 为溶剂， 生成 diammonium fumarate
  参考文献：
  名称：

  一种有机金属盐添加剂的制备方法

  摘要：

  本发明公开一种有机金属盐添加剂的制备方法，步骤如下：（1）以短链有机酸为酸源，氨水为碱源，将两者在水溶液中混合，制备有机酸铵；（2）将铁源或者钙源或者锌源与步骤（1）所得溶液混合、搅拌、过滤、洗涤、干燥，得到高纯度的有机金属盐添加剂。本发明有机金属盐具有较好的晶型结构和较高的纯度，所用原材料来源广泛，价格低廉，较好地解决了现有工艺复杂、生产成本高和产率低等问题，具有良好的工业应用前景。

  公开号：

  CN111138271A

文献信息

• METHOD OF PRODUCING A CARBOXYLIC ALKYL ESTER
  申请人：Bauduin Christophe

  公开号：US20090137825A1

  公开（公告）日：2009-05-28

  The present invention relates to a novel process for preparing alkyl polycarboxylates from an aqueous solution of an ammonium salt of the polycarboxylic acid by reactive distillation, and to a process for hydrogenating the alkyl carboxylates prepared in this way.

  本发明涉及一种从多羧酸铵盐水溶液出发，通过反应蒸馏制备烷基多羧酸酯的新工艺，以及一种氢化以这种方式制备的烷基羧酸酯的过程。
• Coerced photodimerization reaction in the solid state through amine salt formation
  作者：Yoshikatsu Ito、Tetsuya Kitada、Masahiro Horiguchi

  DOI：10.1016/s0040-4020(03)01140-2

  日期：2003.9

  Photodimerization of fumaric or several γ-form trans-cinnamic acids proceeded successfully in the solid state through amine salt formation with ammonia or some aromatic heterocyclic amines (especially, imidazole). It appears that this success is due to a small size or a planar structure of the amine. A layered or a channel-type clathrate crystal structure was revealed, respectively.

  通过与氨或某些芳香族杂环胺（尤其是咪唑）形成胺盐，富马酸或几种γ型反式肉桂酸的光致二聚反应在固态下成功进行。看来这种成功是由于胺的尺寸小或平面结构。分别显示出层状或沟道型包合物晶体结构。
• METHOD FOR PREPARING AMMONIUM SALTS OF FUMARIC OR SUCCINIC ACID
  申请人：Trunin Roman Anatolievich

  公开号：US20120130125A1

  公开（公告）日：2012-05-24

  An improved process for preparing ammonium salts from fumaric or succinic acid, is described. The method consists of neutralizing the corresponding acid carbonate or ammonium bicarbonate at a molar stoichiometric or greater than the stoichiometric ratio of 4-5% in a saturated aqueous solution of the synthesized salt at a temperature not exceeding 40° C., followed by separation of the product and drying at a temperature not exceeding 70° C. After separation of the ammonium salts, the filtrate can be re-used. Isolation of the product is usually carried out by cooling the reaction mixture to a temperature of 15-18C°. The product comes out in almost crystalline form. Saturated aqueous solution of the synthesized salt is formed by the interaction of carbonate or ammonium bicarbonate with the appropriate acid at a temperature not exceeding 40° C. It is possible to obtain cleaner salt concentration weighing more than 99% and not yielding lower than 98%. The method allows for an increase in the yield of targeted products and ensures their consistent high quality due to their formation in crystalline form.

  描述了一种从富马酸或琥珀酸制备铵盐的改进过程。该方法包括在不超过40°C的饱和水溶液中，中和相应的酸碳酸盐或氢碳酸铵，摩尔配比或大于4-5%的摩尔配比，然后将产物分离并在不超过70°C的温度下干燥。在分离铵盐后，可以重新使用滤液。通常通过将反应混合物冷却至15-18°C的温度来分离产物。产物以几乎结晶形式出现。通过碳酸盐或氢碳酸铵与适当酸之间的相互作用，在不超过40°C的温度下形成合成盐的饱和水溶液。可以获得纯净度超过99%且产率不低于98%的盐浓度。该方法可以增加目标产品的产量，并通过以结晶形式形成来确保其始终具有高质量。
• Preparation of salt of polyaspartic acid by high temperature reaction
  申请人：Srchem Incorporated

  公开号：US05288783A1

  公开（公告）日：1994-02-22

  Polyaspartate, useful or inhibition of incrustations due to materials causing hardness in water and of value in detergent formulations, can be prepared by reacting maleic acid or fumaric acid in a molar ratio of 1:1-2.1 at temperatures greater than 170.degree. C., followed by conversion of the polymer formed in this reaction to a salt of polyaspartic acid by basic hydrolysis.

  聚天冬氨酸（Polyaspartate）是一种有用的物质，可以抑制水中硬度物质引起的结垢，并在清洁剂配方中具有价值。它可以通过在大于170°C的温度下以1:1-2.1的摩尔比反应丙烯酸或反式丁烯二酸，然后通过碱性水解将反应形成的聚合物转化为聚天冬氨酸盐来制备。
• Preparation of polyaspartic acid by high temperature reaction
  申请人：Srchem Incorporated

  公开号：US05367047A1

  公开（公告）日：1994-11-22

  Polyaspartate, useful for inhibition of incrustations due to materials causing hardness in water and of value in detergent formulations, can be prepared by reacting maleic acid or fumaric acid in a molar ratio of 1:1-2.1 at temperatures greater than 190.degree. C., followed by conversion of the polymer formed in this reaction to a salt of polyaspartic acid by basic hydrolysis.

  聚天冬氨酸是一种有用的化合物，可用于抑制因水中硬度物质而引起的结垢，并在洗涤剂配方中具有价值。它可以通过在摩尔比为1:1-2.1的条件下，将马来酸或富马酸在大于190摄氏度的温度下反应，然后通过碱性水解将在该反应中形成的聚合物转化为聚天冬氨酸盐来制备。