| 499219-43-1

• CAS: 499219-43-1
• 化学式: C₇₁H₇₀ClMnN₄O₃
• 分子量: 1117.75
• InChiKey: KPTKHZQACDFANP-CJGWQYIDSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  5-[2,7-di-tert-butyl-5-hydroxycarbonyl-9,9-dimethylxanthen-4-yl]-10,15,20-tris(2,4,6-trimethylphenyl)porphyrin 在 air 、 manganese(II) acetate 、 盐酸 、 sodium chloride 作用下， 以 N,N-二甲基甲酰胺 、 二氯甲烷 为溶剂， 反应 6.0h， 以90%的产率得到
  参考文献：
  名称：

  Proton-Coupled O−O Activation on a Redox Platform Bearing a Hydrogen-Bonding Scaffold

  摘要：

  Porphyrin architectures bearing a hydrogen-bonding scaffold have been synthesized. The H-bond pendant allows proton-coupled electron transfer (PCET) to be utilized as a vehicle for effecting catalytic O-O bond activation chemistry. Suzuki cross-coupling reactions provide a modular synthetic strategy for the attachment of porphyrins to a rigid xanthene or dibenzofuran pillar bearing the H-bond pendant. The resulting HPX (hanging porphyrin xanthene) and HPD (hanging porphyrin dibenzofuran) systems permit both the orientation and acid-base properties of the hanging H-bonding group to be controlled. Comparative reactivity studies for the catalase-like disproportionation of hydrogen peroxide and the epoxidation of olefins by the HPX and HPD platforms with acid and ester hanging groups reveal that the introduction of a proton-transfer network, properly oriented to a redox-active platform, can orchestrate catalytic O-O bond activation. For the catalase and epoxidation reaction types, a marked reactivity enhancement is observed for the xanthene-bridged platform appended with a pendant carboxylic acid group, establishing that this approach can yield superior catalysts to analogues that do not control both proton and electron inventories.

  DOI：

  10.1021/ja028548o