2-carbethoxy-3-methyl-7-(5-carboxypentyl)-1,9-diphenyl-4,4-difluoro-3a,4a,7-triaza-4-bora-cyclopenta[b]fluoren-8-one | 1421833-66-0

• 英文名称: 2-carbethoxy-3-methyl-7-(5-carboxypentyl)-1,9-diphenyl-4,4-difluoro-3a,4a,7-triaza-4-bora-cyclopenta[b]fluoren-8-one
• CAS: 1421833-66-0
• 化学式: C₃₄H₃₂BF₂N₃O₅
• 分子量: 611.453
• InChiKey: BWPBLJCAWKUGML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  2-carbethoxy-3-methyl-7-(5-carboxypentyl)-1,9-diphenyl-4,4-difluoro-3a,4a,7-triaza-4-bora-cyclopenta[b]fluoren-8-one 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  An efficient method of chemical modification of BODIPY core

  摘要：

  A simple approach to the modification of BODIPY nucleus has been developed. The method is based on the reaction of acetaldehyde-substituted dye with primary amines followed by cyclization of enamine intermediates. This procedure allowed preparing a series of new BODIPY derivatives with functional substituents useful for various practical purposes, including bioconjugation and other biomedical applications. The synthesized BODIPYs annealed to a pyridone fragment are stable compounds and intense fluorophores with emission maximum around 615 nm. This lambda(em) may be red-shifted by the introduction of styryl substituent. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.01.050
• 作为产物：
  描述：

  以 水 为溶剂， 生成 2-carbethoxy-3-methyl-7-(5-carboxypentyl)-1,9-diphenyl-4,4-difluoro-3a,4a,7-triaza-4-bora-cyclopenta[b]fluoren-8-one
  参考文献：
  名称：

  An efficient method of chemical modification of BODIPY core

  摘要：

  A simple approach to the modification of BODIPY nucleus has been developed. The method is based on the reaction of acetaldehyde-substituted dye with primary amines followed by cyclization of enamine intermediates. This procedure allowed preparing a series of new BODIPY derivatives with functional substituents useful for various practical purposes, including bioconjugation and other biomedical applications. The synthesized BODIPYs annealed to a pyridone fragment are stable compounds and intense fluorophores with emission maximum around 615 nm. This lambda(em) may be red-shifted by the introduction of styryl substituent. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.01.050