[ZnCl2(1,1′-(anthracen-9-ylmethylene)bis(1H-pyrazole))]2 | 1555898-93-5

• 英文名称: [ZnCl2(1,1′-(anthracen-9-ylmethylene)bis(1H-pyrazole))]2
• 英文别名: [ZnCl₂(1,1′-(anthracen-9-ylmethylene)bis(1H-pyrazole))]₂
• CAS: 1555898-93-5
• 化学式: C₄₂H₃₂Cl₄N₈Zn₂
• 分子量: 921.362
• InChiKey: USKWAXYZQBTJPG-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  1,1'-(anthracen-9-ylmethylene)bis(1H-pyrazole) 、 zinc(II) chloride 以 乙酸乙酯 为溶剂， 反应 3.0h， 生成 [ZnCl2(1,1′-(anthracen-9-ylmethylene)bis(1H-pyrazole))]2
  参考文献：
  名称：

  Synthesis, characterization, cytotoxicity and antibacterial activity of an anthracenyl-linked bis(pyrazolyl)methane ligand and its zinc(II) complexes

  摘要：

  Three novel Zn(II) complexes (1-3) with 1,1'-(anthracen-9-ylmethylene)bis(1H-pyrazole) (L-2) have been prepared and structurally characterized by X-ray crystallography. Among them, 1 is a binuclear Zn(II) complex while 2 and 3 are mononuclear. The in vitro cytotoxic and antibacterial activities of these complexes were also evaluated. The three complexes exhibit cytotoxic specificity and significant antitumor activity. The MIC50 value of complex 1 against Pseudomonas putida reaching 0.011 mu g/mL much lower than that the positive control chloromycin (0.182 mu g/mL), indicates that complex 1 is a potent antibacterial agent. (C) 2013 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2013.10.064