4-Fluoro-1-(4-fluorophenyl)butane-1,3-dione | 415700-99-1

• 英文名称: 4-Fluoro-1-(4-fluorophenyl)butane-1,3-dione
• CAS: 415700-99-1
• 化学式: C₁₀H₈F₂O₂
• 分子量: 198.169
• InChiKey: BFSQDMGDWUKJMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-Fluoro-1-(4-fluorophenyl)butane-1,3-dione 、 copper diacetate 以 甲醇 为溶剂， 以62%的产率得到
  参考文献：
  名称：

  SYNTHESIS OF SOME 1-FLUOROARYL-1,3-DIKETONES, BIS(1,3-DIKETONATO)COPPER(II), BIS(1,3-DIKETONATO)DIOXOURANIUM(VI), AND THEIR ELECTROPHILIC SUBSTITUTION REACTIONS

  摘要：

  Some 1-fluoroaryl-1,3-diketones were prepared by treatment of methyl 1-fluoroaryl ketone with ethyl acetate, ethyl fluoroacetate or ethyl pentafluoropropionate in the presence of sodamide which were characterized in the form of their copper chelates. 1-Substituted-aryl-1,3-diketones (la-h) in turn on treatment with uranyl acetate afforded corresponding bis(1,3-diketonato) dioxouranium(VI) (3a-f). Bis(1,3-diketonato)dioxouranium(VI) (3a-f) when subjected to electrophilic bromination or nitration reactions yielded bis(2-bromo1,3-diketonato)dioxouranium(VI) (4a-e) and bis(2-nitro-I,3-diketonato)dioxouranium(VI) (5a-e), respectively. The bonding mode of the ligands to the uranium ion has also been determined from IR and H-1 NMR spectral studies.

  DOI：

  10.1081/sim-120013154