perfluoro (N-methyl-N-ethyl-n-propylamine) | 107835-86-9

• 英文名称: perfluoro (N-methyl-N-ethyl-n-propylamine)
• 英文别名: perfluoro(methylethyl-n-propylamine)；1,1,2,2,3,3,3-heptafluoro-N-(1,1,2,2,2-pentafluoroethyl)-N-(trifluoromethyl)propan-1-amine
• CAS: 107835-86-9
• 化学式: C₆F₁₅N
• 分子量: 371.049
• InChiKey: VIKVXXRKJJIXHD-UHFFFAOYSA-N

物化性质

• 沸点：
  78.5-79.5 °C
• 密度：
  1.7792 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  perfluoro (N-methyl-N-ethyl-n-propylamine) 在 五氯化钼 硫酸 作用下， 反应 24.0h， 以54.9%的产率得到perfluoro(N-ethyl,N-n-propylcarbamoyl fluoride)
  参考文献：
  名称：

  通过全氟（N，N-二烷基甲基胺）与发烟硫酸的反应合成全氟（N，N-二烯丙基氨基甲酰氟）

  摘要：

  一种方便的一步制备新的全氟（N，N-二烷基氨基甲酰氟）[二烷基：R f = R'f = C 2 F 5（1b）; R f＝ C 2 F 5，R′f＝ C 3 F 7（2b）；ř ˚F = R' ˚F = NC 3 ˚F 7（图3b）; ř ˚F = NC 3 ˚F 7，R' ˚F = NC 4 ˚F 9（图4b）; ř ˚F = NC 3 ˚F 7，R' ˚F = NC 5F 11（5b）；ř ˚F = R' ˚F = NC 4 ˚F 9 6B; ř ˚F = NC 3 ˚F 7，R' ˚F = CF 3（图7b）; R f＝ nC 4 F 9 R′＝ CF 3（8b）；ř ˚F = NC 5 ˚F 11，R' ˚F = CF 3（9B）]中描述了：全氟对应（N，N-dialkylmethylamines）用发烟硫酸处理。催化剂（HgSO 4和MoCl 5）提高了所得产品的收率和纯度。描述

  DOI：

  10.1016/s0022-1139(00)84155-x
• 作为产物：
  描述：

  N-甲基高哌嗪 以18%的产率得到
  参考文献：
  名称：

  BABA HAJIME; ABE TAKASHI; HAYASHI EIJI, J. CHEM. SOC. JAP., CHEM. AND IND. CHEM.,(1986) N 9, 1249-1251

  摘要：

  DOI：

文献信息

• The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of 3-dialkylamino propionic acids
  作者：Takashi Abe、Eiji Hayashi、Haruhiko Fukaya、Yoshio Hayakawa、Hajime Baba、Shigeki Ishikawa、Kinya Asahino

  DOI：10.1016/s0022-1139(00)82821-3

  日期：1992.4

  Six methyl esters of 3-dialkylamino-substituted propionic acids were subjected to electrochemical fluorination to give the corresponding perfluoroacid fluorides. The following dialkylamino substituents were investigated: diethylamino, di-n-propyl-amino, di-n-butylamino, pyrrolidino, morpholino and piperidino groups. These perfluoroacid fluorides, which were obtained in fair yields, are considered to

  将3-二烷基氨基取代的丙酸的六种甲酯进行电化学氟化，得到相应的全氟代氟化物。研究了以下二烷基氨基取代基：二乙基氨基，二正丙基氨基，二正丁基氨基，吡咯烷基，吗啉代和哌啶子基。这些以合理收率获得的全氟酸氟化物被认为是制备软质（可降解）含氟化合物的潜在关键前体。这些盐在水溶液中显示出明显降低的表面张力。报告了所获得的所有全氟酸氟化物的物理性质，以及它们的光谱数据（19 F NMR，质谱和IR光谱）。
• Simons electrochemical fluorination of substituted homopiperazines(hexahydro-1,4-diazepines) and piperazines
  作者：Takashi Abe、Hajime Baba、Haruhiko Fukaya、Masanori Tamura、Akira Sekiya

  DOI：10.1016/s0022-1139(02)00247-6

  日期：2003.1

  Simons electrochemical fluorination (ECF) of 1,4-dimethyl-1,4-homopiperazine, methyl 4-ethylhomopiperazin-1-ylacetate and 1, 4-bis(methoxycarbonylmethyl)-1,4-homopiperazine was studied. For comparison, ECF of three piperazines with a N-(methoxycarbonylmethyl) group(s) was also studied. ECF of 1,4-dimethyl-1,4-homopiperazine gave a low yield of corresponding perfluoro(1,4dimethyl-1,4-homopiperazine) together with perfluoro(2,6-diaza-2,6-dimethylheptane) as the major product. Corresponding perfluoro(homopiperazines) with mono- and/or di-(fluorocarbonyldifluoromethyl) groups [-CF2C(O)F] at the 1- and/or 4-position were formed in low yields from methyl 4-ethylhomopiperazin-1-ylacetate and 1,4-bis(methoxycarbonylmethyl)-1,4-homopiperazine, respectively. These new seven-membered perfluoro(1,4-dialkyl-1,4-homopiperazines) were accompanied by the formation of mono- and/or di-basic linear perfluoroacid fluorides resulting from the C-C bond scission at the 2- and 3-positions of the ring. From mono- and/or di-N-(methoxycarbonylmethyl)-substituted piperazines, corresponding perfluoropeperazines having the acid fluoride group(s) were formed in low yields. (C) 2002 Elsevier Science B.V. All rights reserved.
• ABE, TAKASHI;HAYASHI, EIJI, J. FLUOR. CHEM., 45,(1989) N, C. 293-311
  作者：ABE, TAKASHI、HAYASHI, EIJI

  DOI：——

  日期：——