1-bromogermatrane | 70559-35-2

• 英文名称: 1-bromogermatrane
• 英文别名: bromogermatrane
• CAS: 70559-35-2
• 化学式: C₆H₁₂BrGeNO₃
• 分子量: 298.66
• InChiKey: CEGHJPWVZJVSFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  1-bromogermatrane 、 triethylethoxystannane 以 氯仿 为溶剂， 以92%的产率得到1-ethoxygermatrane
  参考文献：
  名称：

  A facile synthesis of 1-halo- and 1-organoxygermatranes

  摘要：

  Interaction of the readily available 1-trimethylsiloxygermatranes (1a, 1b) with various halogenating reagents (Me3SiBr, Me3SiI, HF and SOCl2) has given the 1-halogermatranes (2a-2f). The 1-halogermatranes (2a, 2b) have been converted into the corresponding 1-organoxygermatranes by treatment with trialkylalkoxystannanes (3a-3f). The corresponding 1-organoxygermatranes (4d, 4e, 4f) were made by interaction of 1-hydroxygermatrane monohydrate with the corresponding hydroxy derivatives).

  DOI：

  10.1016/0022-328x(91)83089-m
• 作为产物：
  描述：

  三乙醇胺 以 乙醇 为溶剂， 生成 1-bromogermatrane
  参考文献：
  名称：

  Germatranes and their quasi and hypo analogs with highly electronegative substituent at the Ge atom

  摘要：

  描述了含有高电负性取代基的 Ge 原子的 germatranes XGe(OCH2CH2)3N (1)、准 germatranes X2Ge(OCH2CH2)2NR (R = H, Me) (2) 和 hypogermatranes X3Ge(OCH2CH2)NH2 (3) 的合成。采用相应的羟基 germatranes 与铵盐的交换反应来制备它们。合成的化合物 1–3 通过红外光谱进行了研究。

  DOI：

  10.1007/s11172-012-0128-0

文献信息

• Synthesis, Structure and Chemical Transformations of Ethynylgermatranes
  作者：Edmunds Lukevics、Pavel Arsenyan、Sergey Belyakov、Olga Pudova

  DOI：10.1002/ejic.200300236

  日期：2003.9

  alkoxylation of chlorogermanes by ethanol in the presence of triethylamine affords triethoxygermanes that then take part in transalkoxylation with triethanolamine to give ethynylgermatranes. The molecular structures of all ethynylgermatranes and the hexacarbonyldicobalt complex of 1-heptynylgermatrane have been determined by X-ray crystallography. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany

  乙炔基锗烷是由单取代乙炔通过三步合成法制备的，无需分离水解不稳定的中间体氯锗烷和乙氧基锗烷。在己烷中煮沸四氯锗烷 Cl4Ge、乙炔 RC≡CH 和三乙胺的等摩尔混合物导致 Csp-H 键的胚芽化和乙炔基取代的三氯锗烷的形成。随后在三乙胺存在下通过乙醇对氯锗烷进行烷氧基化，得到三乙氧基锗烷，然后与三乙醇胺进行烷氧基转移，得到乙炔基锗烷。所有乙炔基锗烷和 1-庚炔基锗烷的六羰基二钴络合物的分子结构都已通过 X 射线晶体学确定。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
• New approach to 1-(phenylethynyl)germatranes and 1-(phenylethynyl)-3,7,10-trimethylgermatrane. Reactions of 1-(phenylethynyl)germatrane with N-bromosuccinimide and bromine
  作者：Sergey S Karlov、Pavel L Shutov、Andrei V Churakov、Jörg Lorberth*、Galina S Zaitseva*

  DOI：10.1016/s0022-328x(01)00708-2

  日期：2001.5

  Reaction of N(CH2CHRO)3GeBr (2a, b) with LiCCPh affords N(CH2CHRO)3GeCCPh (1a, b) (a, R=H; b, R=Me). Compound (1b) was also obtained by treatment of Cl3GeCCPh (3) with N(CH2CHMeOSnEt3)3 (4). (1a) reacts with N-bromosuccinimide to yield N(CH2CH2O)3GeC(Br)2C(O)Ph (5). Cis-N(CH2CH2O)3GeC(Br)C(Br)Ph (6) is formed by the reaction of 1a with Br2 in equivalent amounts. All compounds were characterized

  的N（CH反应2 CHRO）3 GEBR（图2a，2b）与LiCCPh得到N（CH 2 CHRO）3 GeCCPh（1A，b）（一，R = H; b，R = Me）的。化合物（1B）也被处理的Cl得到3 GeCCPh（3）与N（CH 2 CHMeOSnEt 3）3（4）。（1a）与N-溴琥珀酰亚胺反应生成N（CH 2 CH 2 O）3 GeC（Br）2 C（O）Ph（5）。通过1a与等价量的Br 2的反应形成顺式-N（CH 2 CH 2 O）3 GeC（Br）C（Br）Ph（6）。所有化合物均通过1 H-和13 C-NMR光谱和质谱进行表征。通过X射线衍射研究确定了1a和6的单晶结构。
• Gar, T. K.; Khromova, N. Yu.; Tandura, S. N., Journal of general chemistry of the USSR, 1983, vol. 53, p. 1619 - 1626
  作者：Gar, T. K.、Khromova, N. Yu.、Tandura, S. N.、Mironov, V. F.

  DOI：——

  日期：——
• Preparation of germatranyl triflates: reactions of germatranes N(CH2CHRO)3X (X=Br, OTf, OSiMe3; R=H, Me) with lithium reagents
  作者：Sergey S. Karlov、Pavel L. Shutov、Novruz G. Akhmedov、Markus A. Seip、Jörg Lorberth*、Galina S. Zaitseva*

  DOI：10.1016/s0022-328x(99)00739-1

  日期：2000.4

  New germatranes N(CH2CHRO)(3)GeOTf (4a, R = H; 4b, R = Me) were prepared in quantitative yield by treatment of N(CH2CHRO)(3)GeOSiMe3 (2a and 2b), with Me3SiOTf. The reactions of germatranes N(CH2CHRO)(3)GeX [3a, X = Br, R = H; 4a, X = OSO2CF3, R = H; 4b, X = OSO2CF3, R = Me; 2a, X = OSiMe3, R = H; 2b, X = OSiMe3, R = Me] with LiY reagents were studied. A series of germatranes N(CH2CHRO)(3)GeY [5a, R = H, Y = Ind (indenyl); 5b, R = Me, Y = Ind; 6a, R = H, Y = N(SiMe3)(2); 6b, R = Me, Y = N(SiMe3)(2); 7a, R = H, Y = Cp (cyclopentadienyl); 7b, R = Me, Y = Cp; 8a, R = H, Y = Flu (fluorenyl); 9a, R = H, Y = t-Bu] were obtained by nucleophilic substitution with the corresponding LiY reagent. Reactions of N(CH2CHMeO)(3)GeOSiMe3 (2b) and N(CH2CH2O)(3)GeBr (3a) with excess n-BuLi and of N(CH2CH2O)(3)GeOSiMe3 (2a) with excess LiNMe2 led to the formation of n-Bu4Ge and (Me2N)(4)Ge, The structures of new germatranes 4a, 4b, 6b and 7b were confirmed by NMR spectroscopy, mass spectrometry and elemental analyses. (C) 2000 Elsevier Science S.A. All rights reserved.
• Zelchan, G. I.; Lapsinya, A. F.; Solomennikova, I. I., Journal of general chemistry of the USSR, 1983, vol. 53, p. 946 - 952
  作者：Zelchan, G. I.、Lapsinya, A. F.、Solomennikova, I. I.、Lukevits, E.、Liepin'sh, E. E.、Kupche, E. L.

  DOI：——

  日期：——