| 1373953-36-6

• CAS: 1373953-36-6
• 化学式: C₅₄H₆₈O₃P₂Ru
• 分子量: 928.15
• InChiKey: VYIVKACFIXDLET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  五氯酚 、 以 二氯甲烷 为溶剂， 以41%的产率得到
  参考文献：
  名称：

  Synthesis, Characterization, and Reactivity of Ruthenium Bis-Allyl Complexes with Chiral Phosphine-Phosphite Ligands

  摘要：

  A series of ruthenium bis-allyl complexes of formula Ru(eta(3)-2-MeC3H4)(2)(P-OP) (I) which incorporate chiral phosphine-phosphite ligands (P-OP) have been prepared and characterized. Compounds I exist in solution as a mixture of two diastereomers (maj and min) differing in the configuration at the metal. Both isomers are in equilibrium in solution, and their ratio varies with the nature of the P-OP ligand. Along the series, higher values of the maj/min ratio were observed with complexes bearing less sterically encumbered phosphite groups. In reactions of compounds I with protic reagents removal of one or two ally! ligands has been observed. Thus, reaction of 1h with pentachlorophenol produces the mixed allyl-phenoxide 3h, whereas reaction of la or 1h with tiglic acid produces the corresponding tiglates 4a,h, respectively. In addition, compounds I generate active catalysts for the hydrogenation of tiglic and 2-methyl-2-pentenoic acids. By appropriate optimization of the structure of the P-OP ligand, enantioselectivities up to 89% ee were obtained in these reactions. In addition, complexes I also catalyze the ROMP reaction of norbornene, although low initiation rates have been observed for this process.

  DOI：

  10.1021/om300018s
• 作为产物：
  描述：

  [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II) 、 2-(diphenylphosphino)phenyl 3,3',5,5'-tetra-tert-butylbiphenyl-2,2'-diyl phosphite 以 正己烷 为溶剂， 以82%的产率得到
  参考文献：
  名称：

  Synthesis, Characterization, and Reactivity of Ruthenium Bis-Allyl Complexes with Chiral Phosphine-Phosphite Ligands

  摘要：

  A series of ruthenium bis-allyl complexes of formula Ru(eta(3)-2-MeC3H4)(2)(P-OP) (I) which incorporate chiral phosphine-phosphite ligands (P-OP) have been prepared and characterized. Compounds I exist in solution as a mixture of two diastereomers (maj and min) differing in the configuration at the metal. Both isomers are in equilibrium in solution, and their ratio varies with the nature of the P-OP ligand. Along the series, higher values of the maj/min ratio were observed with complexes bearing less sterically encumbered phosphite groups. In reactions of compounds I with protic reagents removal of one or two ally! ligands has been observed. Thus, reaction of 1h with pentachlorophenol produces the mixed allyl-phenoxide 3h, whereas reaction of la or 1h with tiglic acid produces the corresponding tiglates 4a,h, respectively. In addition, compounds I generate active catalysts for the hydrogenation of tiglic and 2-methyl-2-pentenoic acids. By appropriate optimization of the structure of the P-OP ligand, enantioselectivities up to 89% ee were obtained in these reactions. In addition, complexes I also catalyze the ROMP reaction of norbornene, although low initiation rates have been observed for this process.

  DOI：

  10.1021/om300018s

文献信息

• Highly Enantioselective Imine Hydrogenation Catalyzed by Ruthenium Phosphane-Phosphite Diamine Complexes
  作者：Mónica Vaquero、Andrés Suárez、Sergio Vargas、Giovanni Bottari、Eleuterio Álvarez、Antonio Pizzano

  DOI：10.1002/chem.201203193

  日期：2012.12.3

  Mildly does it: A highly enantioselective catalyst for the hydrogenation of N‐aryl imines is described (see scheme). This catalyst offers practical advantages because it operates under very mild conditions and is based on an Ru complex with a diamine as the sole chiral ligand.

  轻度地做：描述了一种用于N-芳基亚胺氢化的高度对映选择性的催化剂（参见方案）。该催化剂具有实际优势，因为它在非常温和的条件下运行，并且基于Ru络合物，其中二胺是唯一的手性配体。