1-deoxy-D-xylulose-5-phosphate synthase | 202218-79-9

• 分子结构分类: 转移酶 - 转移醛基或酮基 - 转酮醇酶和转醛醇酶
• 英文名称: 1-deoxy-D-xylulose-5-phosphate synthase
• 英文别名: 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating)；DXP-synthase；1-deoxy-D-xylulose 5-phosphate synthase from B_. subtilis
• CAS: 202218-79-9

反应信息

• 作为试剂：
  描述：

  乙酸–三乙胺 、 丙酮酸钠-2,3-13C2 、 ¹³C₆-D-glucopyranose 在 1-deoxy-D-xylulose-5-phosphate synthase 、 phosphofructokinase adenosine 5'-triphosphate disodium salt 、 aldolase 、 hexokinase 作用下， 以 水 为溶剂， 反应 12.0h， 以47%的产率得到[U-13C5]1-deoxy-D-xylulose 5-phosphate triethylammonium salt
  参考文献：
  名称：

  Enzyme-Assisted Preparation of Isotope-Labeled 1-Deoxy-d-xylulose 5-Phosphate

  摘要：

  Recombinant l-deoxy-D-xylulose 5-phosphate synthase of Bacillus subtilis was used for the preparation of isotope-labeled 1-deoxy-D-xylulose 5-phosphate using isotope-labeled glucose and/ or isotope-labeled pyruvate as starting materials. The simple one-pot methods described afford almost every conceivable isotopomer of l-deoxy-rt-xylulose 5-phosphate carrying C-13 Or C-14 from commercially available precursors with an overall yield around 50%.

  DOI：

  10.1021/jo0100300